Method of improving the skin barrier function of a pet
View Patent ↗The present invention provides a composition preferably a pet foodstuff comprising pantothenic acid, nicotinamide, histidine, inositol and choline wherein pantothenic acid is provided at a level of 10 mg to 500 mg per 400 kcal per day, its use in the treatment of a skin disorder and methods of controlling a skin disorder. The invention further provides a method of manufacturing a composition of the invention.
1. A method of improving the skin barrier function of a pet comprising administering to the pet a pet foodstuff comprising pantothenic acid, nicotinamide, histidine, inositol and choline wherein pantothenic acid is provided at a level of 10 mg to 500 mg per 400 kcal per day.
2. The method of claim 1 wherein nicotinamide is provided at a level of 25 mg to 800 mg per 400 kcal per day.
3. The method of claim 1 wherein histidine is provided at a level of 10 mg to 10000 mg per 400 kcal per day.
4. The method of claim 1 wherein inositol is provided at a level of 10 mg to 500 mg per 400 kcal per day.
5. The method of claim 1 wherein choline is provided at a level of 10 mg to 700 mg per 400 kcal per day.
6. The method of claim 1 , wherein the skin barrier function is improved by increasing the formation of barrier enhancing lipids in the skin of the pet.
7. The method of claim 1 wherein the skin barrier function is improved by reducing the degree of transepidermal water loss.
8. The method of claim 1 wherein said foodstuff further promotes and/or aids the recovery of the skin from disease and/or trauma.
9. The method of claim 1 , further comprising administering to the pet one or more of pyridoxine, proline, one or more fatty acids or linoleic acid.
10. The method of claim 1 wherein pyridoxine is provided at a level of 1 mg to 500 mg per 400 kcal per day.
11. The method of claim 1 wherein proline is provided at a level of 0.1 g to 20 g per 400 kcal per day.