IP Library Granted Patent US 8,138,224
Granted Patent B2
US 8,138,224 · App. 10/552,723 · Granted Mar 20, 2012

Nutritional or therapeutic composition containing the compound oleuropeine or one of the derivatives thereof

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Quick Facts
Patent No.
US 8,138,224
App. No.
10/552,723
Granted
Mar 20, 2012
Kind
B2
Abstract

The present invention provides a nutritional composition and a pharmaceutical composition to be used for humans or animals comprising as active compound the oleuropein compound or one derivative thereof.

Claims (15)

1. A method for stimulating bone formation and/or inhibiting bone resorption in humans or animals comprising the administration of a composition comprising oleuropein as active compound to a subject in need thereof suffering from a condition selected from the group consisting of type I or type II osteoporosis, secondary osteoporosis, osteolysis observed at the vicinity of a prosthesis, periodontal disease, osteoarthritis, and osteopenia.

2. The method according to claim 1 , wherein the composition is a nutritional composition suitable for oral administration.

3. The method according to claim 2 , wherein the subject in need thereof is suffering from a condition selected from the group consisting of type I or type II osteoporosis, and secondary osteoporosis.

4. The method according to claim 2 , wherein the nutritional composition is selected from the group consisting of food compositions and beverages.

5. The method according to claim 2 , wherein the nutritional composition is a product for animal feeding, in a wet, half-wet, or dry form.

6. The method according to claim 2 , wherein the oleuropein or derivative thereof is an extraction product from a plant belonging to the Oleaceae family.

7. The method according to claim 6 , wherein the extraction product is a product extracted from the stems, the leaves, the fruits or the stones of a plant belonging to the Oleaceae family.

8. The method according to claim 6 , wherein the plant belonging to the Oleaceae family is selected from the group consisting of olea europaea , a plant of genus Ligustrum , a plant of genus Syringa , a plant of genus Fraximus , a plant of genus Jasminum , and a plant of genus Osmanthus.

9. The method according to claim 6 , wherein the extraction product is an olive oil or an oleuropein rich extract of olive oil or leaves.

10. The method according to claim 2 , wherein the nutritional composition is orally administered daily in an amount ranging from 0.01 to 200 mg of the oleuropein or derivative thereof.

11. The method according to claim 1 , wherein the composition is a human or animal pharmaceutical composition.

12. The method according to claim 11 , wherein the pharmaceutical composition is in a suitable form for oral, parenteral, intramuscular or intravenous administration.

13. The method according to claim 11 , wherein the pharmaceutical composition is suitable for a daily oral administration in an amount ranging from 0.01 to 200 mg of the oleuropein or derivative thereof.

14. The method according to claim 4 , wherein the nutritional composition is selected from the group consisting of fruit juices, vegetable juices, oils, butters, margarines, vegetal fats, canned foods, soups, milk-based-foods, ice creams, cheeses, baked products, puddings, confectionary products, cereal bars, breakfast cereals, condiments, and seasoning products.

15. The method according to claim 14 , wherein the nutritional composition is selected from the group consisting of tuna fish in oil, yogurts, cottage cheese, oil-kept cheeses, bread, cookies and cakes, spices and dressings.

Assignments (3)
CORRECTIVE ASSIGNMENT TO CORRECT THE RECEIVING PARTY DATA PREVIOUSLY RECORDED ON REEL 052469 FRAME 0167. ASSIGNOR(S) HEREBY CONFIRMS THE CHANGE OF NAME. Recorded Apr 28, 2020
From: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA)
To: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
Reel/Frame 052510/0160 →
CHANGE OF NAME Recorded Apr 22, 2020
From: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA)
To: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (INRAE)
Reel/Frame 052469/0167 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2012
From: COXAM, VERONIQUE; SKALTSOUNIS, LEANDROS; PUEL, CAROLINE; MAZUR, ANDRE
To: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA)
Reel/Frame 027682/0470 →