IP Library Granted Patent US 7,687,531
Granted Patent B2
US 7,687,531 · App. 10/557,083 · Granted Mar 30, 2010

Iodopyrazolyl carboxanilides

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Quick Facts
Patent No.
US 7,687,531
App. No.
10/557,083
Granted
Mar 30, 2010
Kind
B2
Abstract

This invention relates to novel iodopyrazolylcarboxanilides of the formula (I) in which R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and Z are as defined in the disclosure, to a plurality of processes for preparing these compounds and to their use for controlling unwanted microorganisms. This invention further relates to novel intermediates and their preparation.

Claims (24)

1. An iodopyrazolylcarboxanilide of formula (I)

in which

R 1 , R 2 , R 3 , and R 4 independently of one another represent hydrogen, fluorine, chlorine, methyl, isopropyl, or methylthio,

R 5 represents hydrogen, C 1 -C 8 -alkyl or C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl; represents C 1 -C 6 -haloalkyl or halo-C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl having 1 to 9 fluorine, chlorine, and/or bromine atoms; or represents —COR 7 ,

R 6 represents C 1 -C 3 -alkyl, C 1 -C 2 -alkoxy-C 1 -C 2 -alkyl, or C 1 -C 3 -haloalkyl having 1 to 7 fluorine, chlorine, and/or bromine atoms,

R 7 represents hydrogen, C 1 -C 8 -alkyl, C 1 -C 8 -alkoxy, C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl, or C 3 -C 8 -cycloalkyl; represents C 1 -C 6 -haloalkyl, C 1 -C 6 -haloalkoxy, halo-C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl, or C 3 -C 8 -halocycloalkyl having 1 to 9 fluorine, chlorine, and/or bromine atoms; or represents —COR 12 ,

R 12 represents hydrogen, C 1 -C 8 -alkyl, C 1 -C 8 -alkoxy, C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl, or C 3 -C 8 -cycloalkyl; or represents C 1 -C 6 -haloalkyl, C 1 -C 6 -haloalkoxy, halo-C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl, or C 3 -C 8 -halocycloalkyl having 1 to 9 fluorine, chlorine, and/or bromine atoms, and

Z represents unsubstituted C 2 -C 20 -alkyl or represents C 1 -C 20 -alkyl that is mono- or polysubstituted by identical or different substituents selected from the group consisting of halogen and C 3 -C 6 -cycloalkyl, where the cycloalkyl moiety is optionally mono- or polysubstituted by identical or different substituents selected from the group consisting of halogen and C 1 -C 4 -alkyl.

2. An iodopyrazolylcarboxanilide of formula (I) as claimed in claim 1 in which

R 1 , R 2 , R 3 and R 4 independently of one another represent hydrogen, fluorine, chlorine, or methyl,

R 5 represents hydrogen, C 1 -C 6 -alkyl or C 1 -C 3 -alkoxy-C 1 -C 3 -alkyl; represents C 1 -C 4 -haloalkyl or halo-C 1 -C 3 -alkoxy-C 1 -C 3 -alkyl having 1 to 9 fluorine, chlorine, and/or bromine atoms; or represents —COR 7 ,

R 6 represents methyl, ethyl, isopropyl, monofluoromethyl, difluoromethyl, or trifluoromethyl,

R 7 represents hydrogen, C 1 -C 6 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 3 -alkoxy-C 1 -C 3 -alkyl, or C 3 -C 6 -cycloalkyl; represents C 1 -C 4 -haloalkyl, C 1 -C 4 -haloalkoxy, halo-C 1 -C 3 -alkoxy-C 1 -C 3 -alkyl, or C 3 -C 6 -halocycloalkyl having in each case 1 to 9 fluorine, chlorine, and/or bromine atoms; or represents —COR 12 ,

R 12 represents hydrogen, C 1 -C 6 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 3 -alkoxy-C 1 -C 3 -alkyl, or C 3 -C 6 -cycloalkyl; represents C 1 -C 4 -haloalkyl, C 1 -C 4 -haloalkoxy, halo-C 1 -C 3 -alkoxy-C 1 -C 3 -alkyl, or C 3 -C 6 -halocycloalkyl having 1 to 9 fluorine, chlorine, and/or bromine atoms, and

Z represents unsubstituted C 2 -C 20 -alkyl or represents C 1 -C 20 -alkyl that is mono-or polysubstituted by identical or different substituents selected from the group consisting of fluorine, chlorine, bromine, iodine, and C 3 -C 6 -cycloalkyl, where the cycloalkyl moiety is optionally mono- to tetrasubstituted by identical or different substituents selected from the group consisting of fluorine, chlorine, bromine, iodine, C 1 -C 4 -alkyl, and C 1 -C 4 -haloalkyl.

3. A composition for controlling unwanted microorganisms comprising one or more iodopyrazolylcarboxanilides of formula (I) as claimed in claim 1 and one or more extenders and/or surfactants.

4. A hydroxyalkyliodopyrazolylcarboxanilide of formula (VIII)

in which

R 1 , R 2 , R 3 , and R 4 independently of one another represent hydrogen, fluorine, chlorine, methyl, isopropyl, or methylthio,

R 5 represents hydrogen, C 1 -C 8 -alkyl or C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl; represents C 1 -C 6 -haloalkyl or halo-C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl or represents —COR 7 ,

R 6 represents C 1 -C 3 -alkyl, C 1 -C 2 -alkoxy-C 1 -C 2 -alkyl, or C 1 -C 3 -haloalkyl having 1 to 7 fluorine, chlorine, and/or bromine atoms,

R 7 represents hydrogen, C 1 -C 8 -alkyl, C 1 -C 8 -alkoxy, C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl, or C 3 -C 8 -cycloalkyl; represents C 1 -C 6 -haloalkyl, C 1 -C 6 -haloalkoxy, halo-C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl, or C 3 -C 8 -halocycloalkyl having 1 to 9 fluorine, chlorine, and/or bromine atoms; or represents —COR 12 ,

R 12 represents hydrogen, C 1 -C 8 -alkyl, C 1 -C 8 -alkoxy, C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl, or C 3 -C 8 -cycloalkyl; or represents C 1 -C 6 -haloalkyl, C 1 -C 6 -haloalkoxy, halo-C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl, or C 3 -C 8 -halocycloalkyl having 1 to 9 fluorine, chlorine, and/or bromine atoms, and

X 5 represents C 2 -C 20 -hydroxyalkyl that is optionally additionally mono- or polysubstituted by identical or different substituents selected from the group consisting of halogen and C 3 -C 6 -cycloalkyl, where the cycloalkyl moiety is optionally substituted by halogen and/or C 1 -C 4 -alkyl.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 10, 2018
From: BAYER CROPSCIENCE AG
To: BAYER INTELLECTUAL PROPERTY GMBH
Reel/Frame 045034/0468 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 23, 2006
From: DUNKEL, RALF; ELBE, HANS-LUDWIG; GREUL, JORG NICO; HARTMANN, BENOIT; WACHENDORFF-NEUMANN, ULRIKE; DAHMEN, PETER; KUCK, KARL-HEINZ
To: BAYER CROPSCIENCE AG
Reel/Frame 017707/0810 →