Medicament container

1 . A receptacle for holding a medicament, the receptacle comprising a cavity provided with a raised ridge.

2 . A receptacle according to claim 1 characterised in that the raised ridge is adapted to split air flow into two substantially equal portions.

3 . A receptacle according to claim 1 characterised in that the raised ridge is traverses the radius of the receptacle.

4 . A receptacle according to claims 1 or 3 characterised in that the raised ridge is an arcuate ridge.

5 . A receptacle according to claim 1 characterised in that the ridge traverses a region of the receptacle without contacting the walls of the receptacle.

6 . A receptacle according to claim 1 characterised in that the ridge is substantially diametrical.

7 . A receptacle according to claim 1 characterised in that the height of the ridge is such that the ridge extends substantially to the top of the receptacle.

8 . A receptacle according to claim 1 characterised in that the upper surface of the ridge lies below the top of the receptacle.

9 . A receptacle according to claim 1 characterised in that a frangible sealing member is fixed to the upper part of the receptacle.

10 . A receptacle according to claim 9 characterised in that the frangible sealing member comprises a material which is substantially impermeable to moisture and/or is moisture resistant.

11 . A receptacle according to claim 10 characterised in that the frangible sealing member comprises a plastics film or foil.

12 . A receptacle according to claim 11 characterised in that the frangible sealing member comprises an aluminium foil material.

13 . A receptacle according to claim 11 characterised in that the frangible sealing member comprises a plastics material that is heat bonded to the receptacle.

14 . A receptacle according to claim 11 characterised in that the frangible sealing member comprises a foil material that is bonded to the receptacle with an adhesive.

15 . A receptacle according to claim 1 characterised in that a plurality of dosage units is arranged in series.

16 . A cartridge or strip comprising a series of receptacles according to claim 15 .

17 . A delivery device which comprises a receptacle according to claim 1 .

18 . A delivery device according to claim 17 characterised in that the device comprises a housing having a holder that is adapted to receive the receptacle.

19 . A delivery device according to claim 17 characterised in that the delivery device includes means for rupturing a frangible cover.

20 . A delivery device according to claim 19 characterised in that the rupturing means comprises a piercing mechanism that is adapted to pierce one or more holes in the cover.

21 . A delivery device according to claim 17 characterised in that the delivery device also includes an air inlet tube.

22 . A delivery device according to claim 17 characterised in that it also includes an extraction tube.

23 . A delivery device according to claim 21 characterised in that the extraction tube and/or the air inlet acts as the piercing member.

24 . A delivery device according to claim 20 characterised in that a separate piercing member and a separate extraction tube are provided.

25 . A delivery device according to claim 1 characterised in that in use the extraction tube is positioned above the ridge.

26 . The delivery device according to any one of claims 21 to 25 wherein a piercing end region of said inlet tube and/or said extraction tube is bent.

27 . The delivery device according to claim 26 wherein said inlet tube is bent to point at least partly away from a central zone of a receptacle received by said delivery device.

28 . The delivery device according to claim 27 wherein said inlet tube is bent so as to induce swirl flow of air and medicament in said receptacle.

29 . The delivery device according to claim 26 wherein said inlet tube is bent to point at least partly towards a central zone of a receptacle received by said delivery device.

30 . The delivery device according to claim 29 wherein said inlet tube is bent to cause air flow to be split at an angle in the direction of the extraction tube.

31 . The delivery device according to any one of claims 26 to 30 wherein an angle of curvature of the bent portion of the inlet tube is between 1 and 90°.

32 . The delivery device according to claim 26 wherein a piercing end region of said extraction tube is bent either towards or away from a central zone of a receptacle received by said delivery device.

33 . A delivery device according to claim 17 characterised in that the device is a powder delivery device.

34 . A delivery device according to claim 17 characterised in that the delivery device is an inhaler.

35 . A delivery device according to claim 34 characterised in that the inhaler is a dry powder inhaler.

36 . A delivery device according to claim 34 characterised in that the inhaler comprises a plurality of medicament receptacles.

37 . A delivery device according to claim 36 characterised in that each receptacle houses two medicaments.

38 . A delivery device according to claim 37 characterised in that each medicament is held at either side of the ridge.

39 . A delivery device according to claim 17 characterised in that the device is provided with suitable indexing means.

40 . A receptacle according to claim 1 characterised in that the medicament is a powder.

41 . A receptacle according to claim 40 characterised in that the powder is selected from the group of drugs for the treatment of asthma, COPD or respiratory infections such as β 2 -agonists, e.g. fenoterol, formoterol, pirbuterol, reproterol, rimiterol, salbutamol, salmeterol and terbutaline; non-selective beta-stimulants such as isoprenaline; xanthine bronchodilators, e.g. theophylline, aminophylline and choline theophyllinate; anticholinergics, e.g. ipratropium bromide; mast cell stabilisers, e.g. sodium cromoglycate and ketotifen; bronchial anti-inflammatory agents, e.g. nedocromil sodium; and steroids, e.g. beclomethasone dipropionate, fluticasone, budesonide, flunisolide and ciclesonide, and isomers and/or salts or derivatives thereof.

42 . A receptacle according to claim 41 characterised in that receptacle comprises a combination of medicaments, selected from steroids, such as, beclomethasone dipropionate and formoterol; beclomethasone dipropionate and salmeterol; fluticasone and formoterol; fluticasone and salmeterol; budesonide and formoterol; budesonide and salmeterol; flunisolide and formoterol; and flunisolide and salmeterol.

43 . A receptacle according to claim 40 characterised in that the receptacle comprises a systemically active materials, such as, proteinaceous compounds and/or macromolecules, for example, hormones and mediators, such as insulin, human growth hormone, leuprolide and alpha interferon; growth factors, anticoagulants, immunomodulators, cytokines and nucleic acids.

44 . A method of delivering a medicament which comprises the use of a delivery device according to claim 17 .

45 . A method according to claim 44 characterised in that the medicament is a powder.

46 . A method of treatment of a patient with a respiratory disorder which comprises the administration of a medicament using a delivery device according to claim 17 .

47 . A method according to claim 46 characterised in that the medicament is a powder.

48 . A method of treatment of a patient with a systemic disorder which comprises the administration of a medicament using a delivery device according to claim 17 .

49 . A method of delivering a powder which comprises the use of a delivery device according to claim 17 .

50 . A receptacle or a delivery device substantially as described with reference to the accompanying drawings.