IP Library Granted Patent US 7,254,503
Granted Patent B2
US 7,254,503 · App. 10/560,440 · Granted Aug 7, 2007

Light source wavelength correction

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Quick Facts
Patent No.
US 7,254,503
App. No.
10/560,440
Granted
Aug 7, 2007
Kind
B2
Abstract

A wavelength correction function provides corrected reflectance values from actual reflectance values taken in a reflectance-base instrument. The correction is provided as a function of measured reflectance values and a predefined set of high resolution reflectance values established for the reflectance-based instrument implementing the wavelength correction function.

Claims (330)

1. A method of correcting one or more reflectance values when a center wavelength of one or more light sources used to generate corresponding light signals is different from a specified center wavelength for the one or more light sources, the method comprising the steps of:

A. defining, for each of the one or more light sources, a reference spectral distribution {L*} that is characteristic of the one or more light sources and composed of reference light intensity values over a set of reference wavelengths;

B. defining, for each of the one or more light sources, a spectral distribution {L} comprising actual light intensity values over the set of wavelengths;

C. determining the actual reflectance R of a set of reflected signals;

D. defining a set of detector sensitivity data {D} corresponding to the set of detectors receiving the set of reflected signals;

E. determining high resolution reflectance values {r};

F. determining a correction factor as a function of {L}, {L*}, {r} and {D}; and

G. applying the correction factor to R to determine R*.

2. The method of claim 1 , wherein determining the correction factor in step F is valid up to a range of at least about ±8 nanometers around the specified center wavelength.

3. The method of claim 1 , wherein the one or more light sources comprise LEDs.

4. The method of claim 1 , wherein at least one of the one or more light sources is an infrared light source and determining {r} in step E comprises measuring reflectance values R IR in the infrared range and determining r IR as a constant representing an average of R IR , where each value in {r} equals the value of (R/R IR )·r IR at a corresponding wavelength.

5. The method of claim 4 , wherein the values of {r} are determined at discrete wavelength intervals.

6. The method of claim 1 , wherein the one or more light sources and set of detectors comprise part of a reflectometer.

7. The method of claim 1 , wherein determining a correction factor as a function of {L}, {L*}, {r} and {D} comprises determining a correction factor

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8. A center wavelength correction system configured to correct one or more reflectance values when a center wavelength of one or more light sources used to generate corresponding light signals is different from a specified center wavelength for the one or more light sources, the system comprising:

A. a spectral distribution module configured to determine, for each of the one or more light sources, a spectral distribution {L} comprising actual light intensity values over the set of wavelengths;

B. a reflectance module configure to determine actual reflectance R from a set of reflected signals;

C. at least one storage device comprising:

1) for each of the one or more light sources, a reference spectral distribution {L* } that is characteristic of the one or more light sources and composed of reference light intensity values over a set of reference wavelengths;

2) high resolution reflectance values {r}; and

3) detector sensitivity data {D} corresponding to the set of detectors receiving the set of reflected signals;

D. a correction function module configured to determine a correction factor at a given wavelength as a function of {L}, {L*}, {r} and {D} and to apply the correction factor to R to determine R*.

9. The system of claim 8 , wherein the correction function module is configured to determine the correction factor within a range of at least about ±8 nanometers around the specified center wavelength.

10. The system of claim 8 , wherein the one or more light sources comprise LEDs.

11. The system of claim 8 , wherein at least one of the one or more light sources is an infrared light source and the correction function is configured to determine {r} as a function of measured reflectance values R IR an the infrared range and a constant r IR that represents an average of R IR , where each value in {r} equals the value of (R/R IR )r IR at a corresponding wavelength.

12. The system of claim 11 , wherein the values of {r} are determined at discrete wavelength intervals.

13. The system of claim 8 , wherein the one or more light sources and set of detectors comprise part of a reflectometer.

14. The system of claim 8 , wherein the correction function module is configured to determine a correction factor

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15. A wavelength correction means for correcting one or more reflectance values when a center wavelength of one or more light sources used to generate corresponding light signals is different from a specified center wavelength for the one or more light sources, the system comprising:

A. a spectral distribution means for determining, for each of the one or more light sources, a spectral distribution {L} comprising actual light intensity values over the set of wavelengths;

B. a reflectance means for determining actual reflectance R from a set of reflected signals;

C. at least one storage means far storing:

1) for each of the one or more light sources, a reference spectral distribution {L} that is characteristic of the one or more light sources and composed of reference light intensity values over a set of reference wavelengths;

2) high resolution reflectance values {r}; and

3) detector sensitivity data {D} corresponding to the set of detectors receiving the set of reflected signals;

D. a correction function means for determining a correction factor at a given wavelength as a function of {L}, {L*}, {r} and {D} and to apply the correction factor to R to determine R*.

16. The means of claim 15 , wherein the correction function means includes means for determining the correction factor within a range of at least about ±8 nanometers around the specified center wavelength.

17. The means of claim 15 , wherein the one or more light sources comprise LEDs.

18. The system of claim 15 , wherein at least one of the one or more light sources is an infrared light source and the correction function means includes means for determining {r} as a function of measured reflectance values R IR in the infrared range and a constant r IR that represents an average of R IR , where each value in {r} equals the value of (R/R IR )r IR at a corresponding wavelength.

19. The system of claim 18 , wherein the correction function means includes means for determining values of {r} at discrete wavelength intervals.

20. The system of claim 15 , wherein wavelength correction means comprises a portion of a reflectometer means.

21. The wavelength correction means of claim 15 , wherein the correction function means is configured to determine a correction factor

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22. A reflectometer comprising:

A. a set of light sources;

B. a set of detectors;

C. a reflectance assembly configured to direct light signals from the set of light sources onto a test product and to direct light signals reflected from the test product onto the set of detectors;

D. at least one storage device configured to store a reference spectral distribution {L*}, a set of high resolution reflectance values {r}, a set of detector sensitivity data {D} corresponding to the set of detectors, a measured spectral distribution {L} corresponding tote set of light sources, and a set of measured reflectance values R; and

E. a correction function module for determining a correction factor at a given wavelength as a function of {L}, {L*}, {r} and {D} and to apply the correction factor to R to determine R*.

23. The reflectometer of claim 22 , wherein the set of light sources comprises a set of LEDs.

24. The reflectometer of claim 22 , wherein the correction function module is configured to determine a correction factor

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25. A wavelength correction module, in a reflectance-based system comprising a set of light sources, a set of detectors, and a reflectance assembly configured to direct light signals from the set of light sources onto a test product and to direct light signals reflected from the test product onto the set of detectors, the wavelength correction module comprising:

A. at least one storage device configured to store a reference spectral distribution {L*}, a set of high resolution reflectance values {r}, a set of detector sensitivity data {D} corresponding to the set of detectors, a measured spectral distribution {L} corresponding to the set of light sources, and a set of measured reflectance values R; and

B. a correction function module for determining a correction factor at a given wavelengths a function of {L}, {L*}, {r} and {D} and to apply the correction factor to R to determine R*.

26. The wavelength correction module of claim 25 , wherein the set of light sources comprises a set of LEDs.

27. The wavelength correction module of claim 25 , wherein the correction function module is configured to determine a correction factor

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Assignments (3)
CHANGE OF NAME Recorded Aug 22, 2008
From: SIEMENS MEDICAL SOLUTIONS DIAGNOSTICS
To: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Reel/Frame 021423/0942 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 30, 2007
From: BAYER HEALTHCARE LLC
To: SIEMENS MEDICAL SOLUTIONS DIAGNOSTICS
Reel/Frame 019769/0510 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 6, 2006
From: HOWARD, III, WILLIS E.
To: BAYER HEALTHCARE, LLC
Reel/Frame 017758/0069 →