Use of Surfactant Preparations for the Treatment of Surgical Adhesions
The invention describes the use of surfactant comprising phospholipids and pulmonary surfactant proteins for the treatment of surgical adhesions.
1 - 6 . (canceled)
7 . A method for treating surgical adhesions in a patient in need thereof comprising the step of:
administering a surfactant preparation comprising at least one phospholipid, surfactant protein and optionally excipients to the patient in need thereof.
8 . The method according to claim 7 , wherein the surfactant preparation is administered topically.
9 . A pharmaceutical composition comprising a surfactant preparation suited for a method of claim 7 , wherein the surfactant preparation comprises at least one phospholipid, pulmonary surfactant proteins SP-B and/or SP-C and/or modified derivatives thereof, and optionally excipients.
10 . A commercial product comprising:
a customary secondary packaging,
a primary packaging comprising a pharmaceutical preparation of at least one phospholipid and surfactant protein SP-B and/or SP-C and, optionally,
a package insert,
the pharmaceutical preparation being suitable for treatment of surgical adhesions in patients in need thereof.
11 . A pharmaceutical composition comprising a surfactant preparation suited for the method of claim 8 , wherein the surfactant preparation comprises at least one phospholipid, pulmonary surfactant proteins SP-B and/or SP-C and/or modified derivatives thereof, and optionally excipients.
12 . The method according to claim 7 , wherein the surfactant protein is recombinantly prepared pulmonary surfactant protein.
13 . The method according to claim 7 , wherein the surfactant protein is a modified derivative of a pulmonary surfactant protein.
14 . The method according to claim 12 , wherein the pulmonary surfactant protein is rSP-C (FF/I).
15 . The method according to claim 7 , wherein the surfactant preparation is in the form of a powder.
16 . The method according to claim 15 , wherein the powder is obtainable by spray-drying.