IP Library Granted Patent US 8,800,555
Granted Patent B2
US 8,800,555 · App. 10/570,034 · Granted Aug 12, 2014

Delivery devices

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Quick Facts
Patent No.
US 8,800,555
App. No.
10/570,034
Granted
Aug 12, 2014
Kind
B2
Abstract

A delivery device for and method of delivering a substance, the delivery device having an outlet member through which substance is in use delivered in an entraining gas flow, and a substance supply unit for supplying substance to be entrained by an entraining gas flow as one or both of a vapor or a fine aerosol mist, wherein the substance supply unit has a flow channel which is fluidly connected to the outlet member, and a substance supporting element for supporting substance, at least a surface of which is in use disposed in the flow channel.

Claims (10)

1. A delivery device, comprising: an outlet member through which substance is in use delivered in an entraining gas flow; and a substance supply unit for supplying the substance to be entrained by the entraining gas flow as one or both of a vapor or a fine aerosol mist, wherein the substance supply unit comprises a flow channel which is fluidly connected to the outlet member through which the entraining gas flow is in use delivered and defines a receiving chamber for receiving a substance dosing unit, wherein the substance supply unit further comprises a dosing member which is movable between a first, open position which allows for introduction of the substance dosing unit into the receiving chamber and a second, closed position in which the receiving chamber is enclosed, and wherein the substance dosing unit comprises a flexible cartridge which contains the substance and is openable to enable release of the contained substance, wherein the cartridge comprises a body having two closure elements which normally close the body and are ruptured to enable release of the contained substance, and the dosing member is configured to open the cartridge during movement of the dosing member to the closed position by squeezing the cartridge and rupturing the closure elements, such that the entraining gas flow is adapted to be delivered through the cartridge from one closure element to the other closure element.

2. The delivery device of claim 1 , wherein the cartridge includes a substance supporting element for supporting the substance therewithin.

3. The delivery device of claim 1 , wherein the body is a tubular body.

4. The delivery device of claim 3 , wherein the cartridge further comprises a porous, absorbent element which is disposed in the tubular body, over which the entraining gas flow is directed to entrain the substance therefrom.

5. The delivery device of claim 1 , wherein the substance is formulated such as to provide for delivery of the entire dose of the substance in a single operation.

6. The delivery device of claim 1 , wherein the substance supply unit further comprises a one-way inlet valve at an inlet end of the flow channel and a one-way outlet valve at an outlet end of the flow channel, which valves act normally to close the flow channel and prevent the escape of the substance therefrom, and, on exhalation through a mouthpiece, are opened to allow for the delivery of an exhalation air flow, as the entraining gas flow, through the flow channel and the receiving chamber.

7. The delivery device of claim 1 , further comprising:

at least one filter element configured to filter the entraining gas flow.

8. The delivery device of claim 7 , wherein the filter element comprises a first, anti-microbial filter adapted to filter microbes from the entraining gas flow and a second, drying filter adapted to de-humidify the entraining gas flow and thereby promote the uptake of the substance through the flow channel.

9. The delivery device of claim 1 , wherein the body is oversized relative to a diametric dimension of the receiving chamber, such that, on insertion of the substance dosing unit and with closure of the dosing member, the body is squeezed diametrally to rupture the closure elements.

Assignments (9)
RELEASE OF SECURITY INTEREST IN PATENTS RECORDED AT REEL/FRAME 71337/0132 Recorded Mar 17, 2026
From: OAKTREE FUND ADMINISTRATION, LLC
To: OPTINOSE, INC.
Reel/Frame 075101/0804 →
PATENT SECURITY AGREEMENT Recorded Mar 16, 2026
From: OPTINOSE, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
Reel/Frame 075111/0018 →
SECURITY INTEREST Recorded May 22, 2025
From: OPTINOSE, INC.
To: OAKTREE FUND ADMINISTRATION, LLC
Reel/Frame 071337/0132 →
RELEASE OF SECURITY INTEREST Recorded May 21, 2025
From: BIOPHARMA CREDIT PLC, AS COLLATERAL AGENT
To: OPTINOSE INC.
Reel/Frame 071547/0979 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 27, 2022
From: OPTINOSE AS
To: OPTINOSE INC
Reel/Frame 061546/0424 →
SECURITY INTEREST Recorded Sep 13, 2019
From: OPTINOSE AS
To: BIOPHARMA CREDIT PLC, AS COLLATERAL AGENT
Reel/Frame 050371/0913 →
RELEASE OF SECURITY AGREEMENT RECORDED AT REEL 044976 FRAME 0505 Recorded Sep 13, 2019
From: ATHYRIUM OPPORTUNITIES III ACQUISITION LP
To: OPTINOSE AS
Reel/Frame 050371/0894 →
SECURITY INTEREST Recorded Dec 29, 2017
From: OPTINOSE AS
To: ATHYRIUM OPPORTUNITIES III ACQUISITION LP
Reel/Frame 044976/0505 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 11, 2007
From: DJUPESLAND, PER GISLE
To: OPTINOSE AS
Reel/Frame 018744/0679 →