Coated test elements
View Patent ↗The invention concerns coated test elements and in particular test elements comprising a capillary gap which have a hydrophobic structured coating at least in the area surrounding the capillary gap.
1. An analytical test element for determining an analyte in a liquid, the test element comprising:
an inert carrier supporting an application zone for sample material;
a detection zone for determining the analyte;
a channel formed to transport liquid from the application zone to the detection zone; and
a hydrophobic structured surface formed in an area around the application zone, the hydrophobic structured surface comprising elevations and depressions, the height of the elevations ranging from about 50 nm to 100 μm;
whereby, upon dosing of the test element, sample liquid is automatically guided towards the channel and is prevented from adhering to the hydrophobic structured surface formed in the area around the application zone.
2. The test element of claim 1 , wherein the channel has an opening in the area of the application zone and the hydrophobic structured surface is positioned at least around the channel opening.
3. The test element of claim 1 wherein the channel is a capillary channel.
4. The test element of claim 1 wherein an interior of the channel has at least partially a hydrophilic surface.
5. The test element of claim 1 wherein the distance between elevations on the hydrophobic structured surface is about 50 nm to 200 μm.
6. The test element of claim 1 wherein the hydrophobic structured surface has a surface energy of ≦20 mN/m.
7. The test element of claim 1 wherein the hydrophobic structured surface has a contact angle with aqueous systems of ≧120°.
8. The test element of claim 1 wherein the hydrophobic structured surface is immobilized on the test element.
9. The test element of claim 1 wherein the test element is designed to be held within a magazine.
10. The test element of claim 9 wherein the magazine is designed to hold both used and unused test elements.
11. The test element of claim 9 wherein the magazine is located within a measuring device.
12. The test element of claim 11 wherein the measuring device is an optical or electrochemical measuring device.
13. The test element of claim 1 wherein the test element is designed to be contained in a measuring device.
14. The test element of claim 13 wherein the measuring device is an optical or electrochemical measuring device.
15. The test element of claim 1 wherein the test element is formed for determining glucose in blood.
16. A method for the determination of an analyte in a liquid, the method comprising:
applying a sample liquid to a test element having an inert carrier supporting an application zone for sample material, a detection zone for determining the analyte, and a channel formed to transport liquid from the application zone to the detection zone, wherein the test element has a hydrophobic structured surface at least in an area around the application zone, the hydrophobic structured surface comprising elevations and depressions, the height of the elevations ranging from about 50 nm to 100 μm;
using the hydrophobic structured surface to guide the sample towards the channel while preventing the sample from adhering to the hydrophobic structured surface formed in the area around the channel; and
qualitatively determining the analyte present in the sample liquid.
17. The method of claim 16 further comprising quantitatively determining the analyte present in the sample liquid.
18. A method for the determination of an analyte in a liquid, the method comprising:
applying a sample liquid to a test element having an inert carrier, an application zone for sample material, a detection zone for determining the analyte, and a channel formed to transport liquid from the application zone to the detection zone, wherein the test element has a hydrophobic structured surface at least in an area around the application zone, the hydrophobic structured surface comprising elevations and depressions, the height of the elevations ranging from about 50 nm to 100 μm;
using the hydrophobic structured surface to guide the sample towards the channel while preventing the sample from adhering to the hydrophobic structured surface formed in the area around the channel; and
quantitatively determining the analyte present in the sample liquid.