IP Library › Granted Patent US 7,875,604
Granted Patent B2
US 7,875,604 · App. 10/588,444 · Granted Jan 25, 2011

Compounds that inhibit HIV particle formation

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Quick Facts
Patent No.
US 7,875,604
App. No.
10/588,444
Granted
Jan 25, 2011
Kind
B2
Abstract

The present invention describes novel methods of identifying compounds which inhibit HIV particle formation and Rev-dependent HIV production. The present invention also provides methods and compounds for inhibiting HIV particle formation and or treating patients infected with HIV.

Claims (4)

1. A method of inhibiting HIV replication, said method comprising contacting a cell comprising HIV with an effective amount of compound 103833:

3-amino-5-ethyl-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide.

2. The method of claim 1 , wherein said compound inhibits REV function.

3. The method of claim 1 , wherein HIV virion production is dependent on Rev protein expression.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 13, 2011
From: REKOSH, DAVID; HAMMARSKJOLD, MARIE-LOUISE
To: UNIVERSITY OF VIRGINIA
Reel/Frame 026582/0453 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 13, 2011
From: UNIVERSITY OF VIRGINIA
To: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Reel/Frame 026583/0542 →
CONFIRMATORY LICENSE Recorded Jun 2, 2008
From: UNIVERSITY OF VIRGINIA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 021031/0322 →