IP Library Granted Patent US 7,754,253
Granted Patent B2
US 7,754,253 · App. 10/591,582 · Granted Jul 13, 2010

Botulinum toxin for the treatment of reduction of hair growth

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Quick Facts
Patent No.
US 7,754,253
App. No.
10/591,582
Granted
Jul 13, 2010
Kind
B2
Abstract

The use of botulinum toxin for preparing a drug for preventing hair growth is disclosed. A cosmetic method for preventing hair growth is also disclosed.

Claims (18)

1. A method for reducing downy hair growth in a female patient from comprising injecting a therapeutically effective amount of botulinum toxin type A to the area situated between the lips and the nose of said patient.

2. The method for reducing hair growth of claim 1 , wherein the method comprises shaving the area between the lips and the nose of the patient prior to administering the botulinum toxin.

3. The method of claim 1 , wherein the effective amount is from 0.05 to 1 LD 50 units of botulinum toxin type A per cm 2 of skin.

4. The method of claim 3 , wherein the effective amount is from 0.1 to 0.5 LD 50 units of botulinum toxin type A per cm 2 of skin.

5. The method of claim 4 , wherein the effective amount is from 0.2 to 0.4 LD 50 units of botulinum toxin type A per cm 2 of skin.

6. The method of claim 5 , wherein the effective amount is 0.3 LD 50 units of botulinum toxin type A per cm 2 of skin.

7. The method of claim 1 , wherein the botulinum toxin type A is A1.

8. The method of claim 1 , wherein the botulinum toxin type A is A2.

9. A method for reducing downy hair growth in a female patient comprising shaving an area of skin on the patient followed by injecting a therapeutically effective amount of botulinum toxin type A to the shaved area.

10. The method of claim 9 , wherein the area of skin is the face, torso, abdomen, gluteal region, armpits, genitocrural region, legs, or arms.

11. The method of claim 10 , wherein the area of the torso is the breasts.

12. The method of claim 9 , wherein the area of the face is the area situated between the lips and the nose, chin, supraorbital ridge, or cheeks.

13. The method of claim 9 , wherein the effective amount is from 0.05 to 1 LD 50 units of botulinum toxin type A per cm 2 of skin.

14. The method of claim 13 , wherein the effective amount is from 0.1 to 0.5 LD 50 units of botulinum toxin type A per cm 2 of skin.

15. The method of claim 14 , wherein the effective amount is from 0.2 to 0.4 LD 50 units of botulinum toxin type A per cm 2 of skin.

16. The method of claim 15 , wherein the effective amount is 0.3 LD 50 units of botulinum toxin type A per cm 2 of skin.

17. The method of claim 9 , wherein the botulinum toxin type A is A1.

18. The method of claim 9 , wherein the botulinum toxin type A is A2.

Assignments (4)
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNOR NAME PREVIOUSLY RECORDED ON REEL 296336 FRAME 0777. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 5, 2016
From: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S.
To: IPSEN PHARMA S.A.S.
Reel/Frame 037430/0194 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ADDRESS PREVIOUSLY RECORDED ON REEL 023034 FRAME 0251. ASSIGNOR(S) HEREBY CONFIRMS THE ADDRESS SHOULD BE 65 QUAI GEORGES GORSE, 92100 BOULOGNE-BILLANCOURT, FRANCE. Recorded Jan 16, 2013
From: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATION SCIENTIFIQUES (S.C.R.A.S.)
To: IPSEN PHARMA S.A.S.
Reel/Frame 029636/0777 →
CHANGE OF NAME Recorded Jul 31, 2009
From: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATION SCIENTIFIQUES (S.C.R.A.S.)
To: IPSEN PHARMA S.A.S.
Reel/Frame 023034/0251 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 23, 2007
From: LELOUARN, CLAUDE
To: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES
Reel/Frame 019334/0854 →