Method for treating aortic stenosis with non-antibacterial tetracycline formulations
The present invention is for a method for treating aortic stenosis in a mammal in need thereof. The method comprises administering an effective amount of a non-antibacterial tetracycline formulation, to the mammal.
1 . A method for treating aortic stenosis in a mammal in need thereof, the method comprising administering to the mammal an effective amount of a non-antibacterial tetracycline formulation.
2 . The method according to claim 1 , wherein the tetracycline formulation comprises a non-antibacterial amount of an antibacterial tetracycline.
3 . The method according to claim 2 , wherein the antibacterial tetracycline is selected from the group consisting of terramycin, aureomycin, doxycycline, minocycline, tetracycline, oxytetracycline, chlortetracycline, demeclocycline, lymecycline, or pharmaceutically acceptable salts thereof.
4 . The method according to claim 1 , wherein the tetracycline formulation comprises a non-antibacterial tetracycline
5 . The method of claim 4 , wherein the non-antibacterial tetracycline is selected from the group consisting of CMT-1, CMT-2, CMT-4, CMT-6, CMT-7, CMT-9, or CMT-10, or pharmaceutically acceptable salts thereof.
6 . The method of claim 4 , wherein the tetracycline is CMT-3, or its analogs, or pharmaceutically acceptable salts thereof.
7 . The method according to claim 4 , wherein the tetracycline is CMT-8, or its analogs, or pharmaceutically acceptable salts thereof.