Method for producing
View Patent ↗An object of the present invention is to provide a Mallotus philippinensis extract containing readily water soluble rottlerin. A further object of the present invention is to improve convenience at production steps in a method for producing such an extract, by avoiding the staining of filters and/or pipes during extraction and filtration to reduce washing costs, or by facilitating the introduction of freeze drying and so on. When a dye extract is extracted with water and alcohol from a Mallotus philippinensis plant body, the addition of a base component drastically improves the water solubility of the Mallotus philippinensis extract. This improves extraction rates of rottlerin, facilitates washing in the production and the pulverization of the extract, and also improves the water solubility of the obtained extract.
1. A method for producing a Mallotus philippinensis dye composition comprising extracting a Mallotus philippinensis plant body with an alcohol-containing aqueous solvent in the presence of a base component, wherein the Mallotus philippinensis plant body is a powdered kamala.
2. The production method according to claim 1 , wherein the dye composition contains rottlerin as a dye component.
3. The production method according to claim 1 , wherein the solvent has an alcohol concentration of 30 to 90% by volume.
4. The production method according to claim 3 , wherein the solvent has an alcohol concentration of 30 to 70% by volume.
5. The production method according to claim 1 , wherein the base component is at least one base selected from the group consisting of ammonium carbonate, potassium carbonate, sodium carbonate, sodium bicarbonate, tripotassium phosphate, diammonium hydrogen phosphate, dipotassium hydrogen phosphate, disodium hydrogen phosphate, trisodium phosphate, potassium hydroxide, and sodium hydroxide.
6. The production method according to claim 5 , wherein the base component is at least one base selected from the group consisting of sodium bicarbonate, sodium carbonate, and trisodium phosphate.
7. The production method according to claim 6 , wherein the amount of the base component used is 10 to 300% by weight with respect to the amount of the Mallotus philippinensis plant body.
8. The production method according to claim 7 , wherein the amount of the base component used is 10 to 30% by weight with respect to the amount of the Mallotus philippinensis plant body.
9. The production method according to claim 1 , wherein the amount of the solvent used in the extraction is 5 to 20 times by weight larger-than that of the Mallotus philippinensis plant body.
10. The production method according to claim 1 , wherein the extraction is performed under conditions where the solvent in contact with the plant body has a pH of 7.0 or higher.
11. The production method according to claim 10 , wherein the extraction is performed under conditions where the solvent in contact with the plant body has a pH of 7.0 to 11.
12. The production method according to claim 11 , wherein the extraction is performed under conditions where the solvent in contact with the plant body has a pH of 7.0 to 9.0.
13. The production method according to claim 1 , wherein the temperature of the solvent during the extraction is room temperature to reflux temperature.
14. The production method according to claim 13 , wherein the temperature of the solvent during the extraction is 50 to 80° C.
15. A water-soluble Mallotus philippinensis dye composition produced by a production method according to claim 1 , wherein rottlerin contained in the composition has a water solubility of 250 μg/mL-12,750 μg/mL.
16. The dye composition according to claim 15 , wherein the dye composition is used as a coloring agent and/or a preservative agent in foods, drinks, or cosmetics, or used as an anthelmintic.