IP Library Granted Patent US 7,226,455
Granted Patent B2
US 7,226,455 · App. 10/606,634 · Granted Jun 5, 2007

Injector for a flexible implant

Assignee: Corneal Industrie
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Quick Facts
Patent No.
US 7,226,455
App. No.
10/606,634
Granted
Jun 5, 2007
Kind
B2
Abstract

The invention relates to a folder module for folding a flexible intraocular implant for injection into the eye of a patient. The module comprises two jaws that are movable relative to each other, each jaw having a folder wall constituted by a portion of a cylindrical surface, and a plane wall secured to the folder wall, the two plane walls lying in parallel planes; a pivot axis orthogonal to the plane walls to control relative pivoting movement of one jaw relative to the other; one of the jaws being capable of occupying relative to the other a first position in which said plane walls are offset relative to each other; a second position in which the plane walls face each other so as to define an implant confinement volume; and a third position in which the folder walls meet each other to define a folder chamber enabling the implant to be finally folded.

Claims (20)

1. A folder module for folding a flexible intraocular implant for injection into the eye of a patient, the module comprising:

two jaws that are movable relative to each other, each jaw having a folder wall constituted by a portion of a cylindrical surface and a plane wall secured to the folder wall, the two plane walls lying in parallel planes, one of said plane walls forming a bottom plane wall;

a pivot axis orthogonal to the plane walls to control relative pivoting movement of one jaw relative to the other;

one of the jaws being capable of occupying relative to the other jaw a first position in which the plane walls are spaced apart from each other, thereby enabling the implant to be put into place on the bottom plane wall; a second position in which the plane walls face each other, whereby the folder walls and the plane walls define a confinement volume for the implant; and a third position in which the folder walls meet each other so as to define a substantially cylindrical volume forming a folder chamber enabling the implant to be finally folded.

2. A folder module according to claim 1 , wherein the first of said jaws further comprises two side walls parallel to said pivot axis and secured to the edges of the plane wall of said jaw, such that when the two jaws are in their second relative position, the plane walls, the folder walls, and the side walls together define a storage space in which the implant can be held in a non-folded state.

3. A folder module according to claim 2 , wherein the distance between the two plane walls is greater than the thickness of the implant.

4. A folder module according to claim 3 , wherein the distance between the plane walls lies in the range 1 mm to 3 mm.

5. A folder module according to claim 2 , wherein said jaws further comprise means for holding them in their second relative position, whereby the implant can be held in a storage volume.

6. A folder module according to claim 2 , wherein said jaws further comprise holding means for holding them in their third relative position, whereby the implant can be held in the folded state in the folder chamber so as to enable the implant to be injected into the eye of a patient.

7. A folder module according to claim 2 , wherein said first jaw further comprises an injection passage at one of the ends of said folder chamber on an axis that substantially coincides with the axis of the cylindrical volume defined by the folder walls when said two jaws are in their third relative position.

8. A folder module according to claim 7 , wherein said first jaw further comprises a guide passage opening out to the second end of the folder chamber and having the same axis as the folder chamber, and a pusher member slidably mounted in the guide passage for pushing the implant in the folded state into said injection passage.

9. A flexible implant injector comprising: a folder module comprising:

two jaws that are movable relative to each other, each jaw having a folder wall constituted by a portion of a cylindrical surface and a plane wall secured to the folder wall, the two plane walls lying in parallel planes, one of said plane walls forming a bottom plane wall;

a pivot axis orthogonal to the plane walls to control relative pivoting movement of one jaw relative to the other; one of the jaws being capable of occupying relative to the other jaw a first position in which the plane walls are spaced apart from each other, thereby enabling the implant to be put into place on the bottom plane wall; a second position in which the plane walls face each other, whereby the folder walls and the plane walls define a confinement volume for the implant; and a third position in which the folder walls meet each other so as to define a substantially cylindrical volume forming a folder chamber enabling the implant to be finally folded;

said first jaw further comprising: an injection passage at one of the ends of said folder chamber on an axis that substantially coincides with the axis of the cylindrical volume defined by the folder walls when said two jaws are in their third relative position; and a guide passage opening out to the second end of the folder chamber and having the same axis as the folder chamber, and a pusher member slidably mounted in the guide passage for pushing the implant in the folded state into said injection passage;

an injector body including a housing for receiving said folder module, an injection cannula for extending said injection passage when said folder module is in place in said housing, and an axial guide duct for extending said guide passage when said folder module is in place in said housing; and

a piston whose rod is slidably mounted in said axial guide duct, whereby the end of the rod of said piston can co-operate with one end of the pusher member of said folder module.

10. A flexible implant injector comprising: a folder module comprising:

two jaws that are movable relative to each other, each jaw having a folder wall constituted by a portion of a cylindrical surface and a plane wall secured to the folder wall, the two plane walls lying in parallel planes, one of said plane walls forming a bottom plane wall;

a pivot axis orthogonal to the plane walls to control relative pivoting movement of one jaw relative to the other; one of the jaws being capable of occupying relative to the other jaw a first position in which the plane walls are spaced apart from each other, thereby enabling the implant to be put into place on the bottom plane wall; a second position in which the plane walls face each other, whereby the folder walls and the plane walls define a confinement volume for the implant; and a third position in which the folder walls meet each other so as to define a substantially cylindrical volume forming a folder chamber enabling the implant to be finally folded; a cannula extending a first end of said confinement chamber to guide the implant in its folded state; a guide passage extending a second end of said guide chamber; and a piston slidably mounted in said guide passage to push the implant in the folded state from said folder chamber into said cannula.

Assignments (14)
RELEASE OF SECURITY INTEREST Recorded Nov 20, 2025
From: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
To: BAUSCH HEALTH IRELAND LIMITED; BAUSCH HEALTH COMPANIES INC.; BAUSCH HEALTH, CANADA INC.; TECHNOLAS PERFECT VISION GMBH; VALEANT PHARMACEUTICALS LUXEMBOURG S.A R.L.; VALEANT PHARMA POLAND SPOLKA Z ORGANICZONA ODPOWIEDZIALNOSCIA; VALEANT SP. Z.O.O.
Reel/Frame 073637/0222 →
RELEASE OF SECURITY INTEREST Recorded Nov 20, 2025
From: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
To: ATON PHARMA, INC.; BAUSCH & LOMB INCORPORATED; BAUSCH & LOMB PHARMA HOLDINGS CORP.; COMMONWEALTH LABORATORIES, LLC; DOW PHARMACEUTICAL SCIENCES, INC.; ECR PHARMACEUTICALS CO., INC.; LABORATOIRE CHAUVIN S.A.S.; MEDICIS PHARMACEUTICAL CORPORATION; ONPHARMA INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; SALIX PHARMACEUTICALS, LTD.; SALIX PHARMACEUTICALS, INC.; SANTARUS, INC.; SOLTA MEDICAL, INC.; SYNERGETICS USA, INC.; TECHNOLAS PERFECT VISION GMBH; VALEANT CANADA LP; VALEANT PHARMACEUTICALS INTERNATIONAL; VALEANT PHARMACEUTICALS INTERNATIONAL, INC.; VALEANT PHARMACEUTICALS NORTH AMERICA LLC; WIRRA IP PTY LIMITED; VALEANT PHARMA POLAND SP. Z O.O.; VALEANT PHARMACEUTICALS LUXEMBOURG S.A R.L.; VALEANT PHARMACEUTICALS IRELAND LIMITED
Reel/Frame 073637/0001 →
RELEASE OF SECURITY INTEREST Recorded Apr 8, 2025
From: BARCLAYS BANK PLC, AS COLLATERAL AGENT
To: SOLTA MEDICAL, INC.; PRECISION DERMATOLOGY, INC.; BAUSCH HEALTH IRELAND LIMITED (F/K/A/ VALEANT PHARMACEUTICALS IRELAND LIMITED); SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD; SANTARUS, INC.; MEDICIS PHARMACEUTICAL CORPORATION; HUMAX PHARMACEUTICAL S.A.; SOLTA MEDICAL IRELAND LIMITED; BAUSCH & LOMB MEXICO, S.A. DE C.V.; BAUSCH+LOMB OPS B.V.; BAUSCH HEALTH AMERICAS, INC.; BAUSCH HEALTH COMPANIES INC.; BAUSCH HEALTH HOLDCO LIMITED; BAUSCH HEALTH MAGYARORSZAG KFT (A/K/A BAUSCH HEALTH HUNGARY LLC); BAUSCH HEALTH POLAND SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (F/K/A VALEANT PHARMA POLAND SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA); BAUSCH HEALTH US, LLC; BAUSCH HEALTH, CANADA INC. / SANTE BAUSCH, CANADA INC.; ICN POLFA RZESZOW SPOLKA AKCYJNA (A/K/A ICN POLFA RZESZOW S.A.); ORAPHARMA, INC.; PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.); SOLTA MEDICAL DUTCH HOLDINGS B.V.; V-BAC HOLDING CORP.; VRX HOLDCO LLC; 1261229 B.C. LTD.; 1530065 B.C. LTD.
Reel/Frame 070778/0199 →
SECURITY INTEREST Recorded Oct 5, 2021
From: BAUSCH & LOMB IRELAND LIMITED; BAUSCH HEALTH COMPANIES INC.; DR. GERHARD MANN CHEM.-PHARM. FABRIK GMBH; TECHNOLAS PERFECT VISION GMBH
To: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
Reel/Frame 057821/0800 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jul 3, 2019
From: BAUSCH HEALTH IRELAND LIMITED; BAUSCH HEALTH COMPANIES INC.; BAUSCH HEALTH, CANADA INC.; TECHNOLAS PERFECT VISION GMBH; VALEANT PHARMACEUTICALS LUXEMBOURG S.À R.L.; VALEANT PHARMA POLAND SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA; VALEANT SP. Z O. O.
To: THE BANK OF NEW YORK MELLON, AS COLLATERAL AGENT
Reel/Frame 049672/0652 →
SECURITY INTEREST Recorded Feb 26, 2018
From: ATON PHARMA, INC.; BAUSCH & LOMB INCORPORATED; BAUSCH & LOMB PHARMA HOLDINGS CORP.; COMMONWEALTH LABORATORIES, LLC; DOW PHARMACEUTICAL SCIENCES, INC.; ECR PHARMACEUTICALS CO., INC.; LABORATOIRE CHAUVIN S.A.S.; MEDICIS PHARMACEUTICAL CORPORATION; ONPHARMA INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; SALIX PHARMACEUTICALS, LTD.; SALIX PHARMACEUTICALS, INC.; SANTARUS, INC.; SOLTA MEDICAL, INC.; SYNERGETICS USA, INC.; TECHNOLAS PERFECT VISION GMBH; VALEANT CANADA LP; VALEANT PHARMACEUTICALS INTERNATIONAL; VALEANT PHARMACEUTICALS INTERNATIONAL, INC.; VALEANT PHARMACEUTICALS NORTH AMERICA LLC; WIRRA IP PTY LIMITED; VALEANT PHARMA POLAND SP. Z O.O.; VALEANT PHARMACEUTICALS LUXEMBOURG S.A R.L.; VALEANT PHARMACEUTICALS IRELAND LIMITED
To: THE BANK OF NEW YORK MELLON, AS COLLATERAL AGENT
Reel/Frame 045444/0634 →
SECURITY INTEREST Recorded Feb 26, 2018
From: ATON PHARMA, INC.; BAUSCH & LOMB INCORPORATED; BAUSCH & LOMB PHARMA HOLDINGS CORP.; COMMONWEALTH LABORATORIES, LLC; DOW PHARMACEUTICAL SCIENCES, INC.; ECR PHARMACEUTICALS CO., INC.; LABORATOIRE CHAUVIN S.A.S.; MEDICIS PHARMACEUTICAL CORPORATION; ONPHARMA INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; SALIX PHARMACEUTICALS, LTD.; SALIX PHARMACEUTICALS, INC.; SANTARUS, INC.; SOLTA MEDICAL, INC.; SYNERGETICS USA, INC.; TECHNOLAS PERFECT VISION GMBH; VALEANT CANADA LP; VALEANT PHARMACEUTICALS INTERNATIONAL; VALEANT PHARMACEUTICALS INTERNATIONAL, INC.; VALEANT PHARMACEUTICALS NORTH AMERICA LLC; WIRRA IP PTY LIMITED; VALEANT PHARMA POLAND SP. Z O.O.; VALEANT PHARMACEUTICALS LUXEMBOURG S.A R.L.; VALEANT PHARMACEUTICALS IRELAND LIMITED
To: BARCLAYS BANK PLC, AS COLLATERAL AGENT
Reel/Frame 045444/0299 →
CHANGE OF NAME Recorded Jul 21, 2017
From: VALEANT SP. Z.O.O. SP. J.
To: VALEANT PHARMA POLAND SP. ZO.O.
Reel/Frame 043302/0150 →
SECURITY INTEREST Recorded Jul 21, 2017
From: VALEANT PHARMA POLAND SP. Z O.O.
To: THE BANK OF NEW YORK MELLON
Reel/Frame 043066/0863 →
SECURITY INTEREST Recorded Jul 18, 2016
From: ATON PHARMA, INC.; BAUSCH & LOMB INCORPORATED; BAUSH & LOMB PHARMA HOLDINGS CORP.; DENDREON PHARMACEUTICALS, INC.; DOW PHARMACEUTICAL SCIENCES, INC.; MEDICIS PHARMACEUTICAL CORPORATION; OBAGI MEDICAL PRODUCTS, INC.; OMP, INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD; SANTARUS, INC.; SOLTA MEDICAL, INC.; VALEANT CANADA LP, BY ITS GENERAL PARTNER VALEANT CANADA GP LIMITED; VALEANT PHARMACEUTICALS INTERNATIONAL, INC.; VALEANT HOLDINGS IRELAND (AS SUCCESSOR TO VALEANT INTERNATIONAL BERMUDA); VALEANT PHARMACEUTICALS NORTH AMERICA LLC; VALEANT PHARMACEUTICALS IRELAND
To: BARCLAYS BANK PLC
Reel/Frame 039380/0385 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2014
From: CORNEAL INNOVATION
To: VALEANT SP. Z.O.O SP.J
Reel/Frame 034083/0080 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 28, 2014
From: CORNEAL INDUSTRIE
To: CORNEAL INNOVATION
Reel/Frame 034055/0023 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2004
From: JEANNIN, LIONEL
To: CORNEAL INDUSTRIE
Reel/Frame 014962/0731 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 26, 2003
From: JEANNIN, LIONEL; BOS, GILLES
To: CORNEAL INDUSTRIE
Reel/Frame 014228/0542 →
Priority Claims (2)
FR 00 06417 · May 19, 2000 · national
WO PCT/FR01/01510 · May 17, 2001 · international
Continuity (2)
Continuation 1029562200 · Nov 15, 2002
Related Publication 20050251236A1 · Nov 10, 2005