IP Library Granted Patent US 6,939,879
Granted Patent B2
US 6,939,879 · App. 10/609,751 · Granted Sep 6, 2005

Use of R (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol for the treatment of substance induced insomnia

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 6,939,879
App. No.
10/609,751
Granted
Sep 6, 2005
Kind
B2
Abstract

A method of providing symptomatic relief from sleep induced insomnia in a patient comprising administering an effective amount of R-(+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol or a pharmaceutically acceptable salt thereof to a patient in need of such treatment.

Claims (14)

1. A method of providing symptomatic relief from substance induced insomnia in a patient comprising administering to said patient a therapeutically effective amount of R-(+)-α-(2,3-dimethoxphenyl)-1-[2-(4-fluoropheyl)ethyl]-4-piperidinemethanol or a pharmaceutically acceptable salt thereof wherein said substance is selected from the group consisting of caffeine, alcohol, amphetamine, opioids, sedatives, hypnotics and anxiolytics.

2. The method of claim 1 wherein the substance is caffeine.

3. The method of claim 1 wherein wherein the substance is alcohol.

4. The method of claim 1 wherein the substance is amphetamine.

5. The method of claim 1 wherein the substance is an opiod.

6. The method of claim 1 wherein the substance is a sedative.

7. The method of claim 1 wherein the substance is a hypnotic.

8. The method of claim 1 wherein the substance is an anxiolytic.

9. A method of providing symptomatic relief from alcohol induced insomnia in a patient comprising administering to said patient a therapeutically effective amount of R-(+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol or a pharmaceutically acceptable salt thereof.

10. The method of claim 9 wherein alcohol induced insomnia is caused by effects of taking alcohol.

11. The method of claim 9 wherein alcohol induced insomnia is caused by effects of withdrawing from alcohol.

12. A method of providing symptomatic relief from caffeine induced insomnia in a patient comprising administering to said patient a therapeutically effective amount of R-(+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol or a pharmaceutically acceptable salt thereof.

13. The method of claim 12 wherein alcohol induced insomnia is caused by effects of taking caffeine.

14. The method of claim 12 wherein alcohol induced insomnia is caused by effects of withdrawing from caffeine.

Assignments (10)
CORRECTIVE ASSIGNMENT TO CORRECT THE NAME OF THE ASSIGNOR AND THE NAME OF ASSIGNEE PREVIOUSLY RECORDED ON REEL 034566 FRAME 0938. ASSIGNOR(S) HEREBY CONFIRMS THE THE CORRECT NAME OF THE ASSIGNEE SHOULD BE AVENTIS HOLDINGS INC. AND THE CORRECT NAME OF THE ASSIGNEE SHOULD BE AVENTISUB INC.. Recorded Feb 3, 2015
From: AVENTIS HOLDINGS INC.
To: AVENTISUB INC.
Reel/Frame 034891/0063 →
CHANGE OF NAME Recorded Feb 3, 2015
From: AVENTISUB INC.
To: AVENTISUB LLC
Reel/Frame 034891/0100 →
MERGER Recorded Dec 9, 2014
From: AVENTISUB II INC.
To: AVENTIS HOLDINGS INC.
Reel/Frame 034566/0931 →
MERGER Recorded Dec 9, 2014
From: AVENTISUB INC.
To: AVENTISUB II INC.
Reel/Frame 034566/0938 →
MERGER Recorded Dec 9, 2014
From: AVENTIS PHARMACEUTICALS INC.
To: AVENTISUB LLC
Reel/Frame 034566/0958 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 2, 2010
From: AVENTIS HOLDINGS INC.
To: AVENTISUB II INC.
Reel/Frame 024006/0487 →
CHANGE OF NAME Recorded Nov 29, 2007
From: HMR PHARMA INC.
To: AVENTIS HOLDINGS INC.
Reel/Frame 020174/0006 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 16, 2007
From: AVENTIS PHARMACEUTICALS INC.
To: HMR PHARMA INC.
Reel/Frame 020119/0606 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 10, 2005
From: MONDADORI, CESARE; HITCHCOCK, JANICE M.; SORENSEN, STEPHEN
To: HOECHST MARION ROUSSEL, INC.
Reel/Frame 016119/0892 →
CHANGE OF NAME Recorded Jun 10, 2005
From: HOECHST MARION ROUSSEL, INC.
To: AVENTIS PHARMACEUTICALS INC.
Reel/Frame 016119/0925 →