Parasiticidal formulation for animals
View Patent ↗A formulation for treating and preventing parasite infestations in horses, dogs, cats, and other animals is provided. This formulation includes a cestocidal agent, wherein the cestocidal agent is pyrantel, morantel, any salt thereof, or any combination thereof. Preferably the formulation additionally includes an edible non-aqueous liquid and a thickening agent. The formulation of the present invention allows for a high concentration of cestocidal agent.
1. A parasiticidal formulation, comprising:
a cestocidal agent, wherein said cestocidal agent is selected from the group consisting of pyrantel, morantel, and combinations thereof; and
an edible, non-aqueous liquid,
wherein said cestocidal agent is present in said formulation in an amount equal to or greater than about 17% w/w and wherein said formulation comprises no more than about 10% w/w water.
2. The formulation of claim 1 , wherein said cestocidal agent is present in said formulation in an amount between about 17% and about 23% w/w.
3. The formulation of claim 2 , wherein said cestocidal agent is present in said formulation in an amount equal to or greater than about 19% w/w.
4. The formulation of claim 3 , wherein said cestocidal agent is present in said formulation in an amount equal to about 19% w/w.
5. The formulations of claim 2 , wherein said cestocidal agent is present in said formulation in an amount equal to or greater than about 21% w/w.
6. The formulation of claim 5 , wherein said cestocidal agent is present in said formulation in an amount equal to about 21% w/w.
7. The formulation of claim 1 , wherein said cestocidal agent is present as a salt, and said salt is present in said formulation in an amount equal to or greater than about 50% w/w.
8. The formulation of claim 7 , wherein said salt is present in said formulation in an amount between about 50% and about 70% w/w.
9. The formulation of claim 8 , wherein said salt is present in said formulation in an amount between about 50% and about 65% w/w.
10. The formulation of claim 7 , wherein said salt is present in said formulation in an amount equal to about 54% w/w.
11. The formulation of claim 7 , wherein said salt is present in said formulation in an amount equal to about 62% w/w.
12. The formulation of claim 7 , wherein said salt is selected from the group consisting of pyrantel pamoate, pyrantel tartrate and any combination thereof.
13. The formulation of claim 12 , wherein said salt is pyrantel pamoate.
14. The formulation of claim 1 , further comprising:
a thickening agent.
15. The formulation of claim 14 , further comprising:
an agent effective against nematodes and obligate parasitic flies selected from the group consisting of an avermectin, a milbemycin and combinations thereof.
16. The formulation of claim 1 , further comprising:
a preservative.
17. The formulation of claim 1 , wherein said formulation is a paste.
18. The formulation of claim 17 , wherein said formulation is a paste for oral administration.
19. A parasiticidal formulation for oral administration, comprising:
a cestocidal agent, wherein said cestocidal agent is selected from the group consisting of salts of pyrantel and morantel and any combinations thereof; and
an edible, non-aqueous liquid,
wherein said salt is present in said formulation in an amount equal to or greater than 50% w/w and wherein said formulation comprises no more than about 10% w/w water.
20. The formulation of claim 19 , wherein said formulation is a paste.
21. The formulation of claim 20 , wherein said formulation further comprises:
a thickening agent.
22. The formulation of claim 20 , wherein said salt is pyrantel pamoate.
23. A parasiticidal formulation, comprising:
a salt of pyrantel, wherein said salt is present in said formulation in an amount equal to or greater than 50% w/w; and
an edible, non-aqueous liquid,
wherein said formulation is a paste for oral administration and wherein said formulation comprises no more than about 10% w/w water.
24. A method of treating parasite infestations in animals, comprising:
providing a parasiticidal formulation comprising a cestocidal agent selected from the group consisting of pyrantel, morantel, and combinations thereof and an edible, non-aqueous liquid, wherein said cestocidal agent is present in said formulation in an amount equal to or greater than about 17% w/w; and wherein said formulation comprises no more than about 10% w/w water; and
administering said formulation to said animal in a therapeutically effective amount.
25. The method of claim 24 , wherein said formulation is administered to equine to treat Anoplocephala perfoliata infestation.