Granted Patent
B2
US 7,341,867 · App. 10/628,066 · Granted Mar 11, 2008
Human preprotachykinin gene promoter
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Abstract
Compositions and methods are provided for identifying novel therapeutic agents for the treatment of breast cancer, bone marrow metastasis, pain, arthritis, aggressive behavior, depression, and certain hematopoietic disorders. Disclosed are promoters and 3′ regulatory regions of genes whose expression differs in malignant cells as compared with non-malignant cells. These include PPT-I, NK-2 and SP-R.
Claims (3)
1. An isolated nucleic acid molecule comprising SEQ ID NO:1 or SEQ ID NO:14.
2. An expression vector comprising the nucleic acid molecule of claim 1 , operably linked to a heterologous gene that encodes a gene product.
3. An isolated host cell transformed with the vector of claim 2 .
Assignments (1)
NUNC PRO TUNC ASSIGNMENT
Recorded Aug 13, 2014
From: THE UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
To: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
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