Botulinum neurotoxin eluting stent
View Patent ↗The present invention provides for methods of treating cardiovascular diseases in a mammal. The methods include a step of administering an effective amount of a botulinum toxin directly to a blood vessel of a mammal thereby treating a cardiovascular disease.
1. A composition for use in a cardiovascular procedure comprising a stent with a therapeutically affective amount of a botulinum neurotoxin attached or embedded therein wherein the botulinum neurotoxin elutes from the stent.
2. The composition of claim 1 wherein the botulinum neurotoxin is botulinum neurotoxin type A.
3. The composition of claim 1 wherein the botulinum neurotoxin is selected from the group consisting of botulinum neurotoxins A, B, C, D, E, F and G.
4. A self-expanding stent for use in a cardiovascular procedure comprising a therapeutically effective amount of a botulinum neurotoxin attached or embedded therein.
5. An angioplasty balloon for use in a cardiovascular procedure comprising a therapeutically effective amount of a botulinum neurotoxin attached or embedded therein.