IP Library Granted Patent US 7,048,927
Granted Patent B2
US 7,048,927 · App. 10/628,905 · Granted May 23, 2006

Botulinum neurotoxin eluting stent

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Quick Facts
Patent No.
US 7,048,927
App. No.
10/628,905
Granted
May 23, 2006
Kind
B2
Abstract

The present invention provides for methods of treating cardiovascular diseases in a mammal. The methods include a step of administering an effective amount of a botulinum toxin directly to a blood vessel of a mammal thereby treating a cardiovascular disease.

Claims (5)

1. A composition for use in a cardiovascular procedure comprising a stent with a therapeutically affective amount of a botulinum neurotoxin attached or embedded therein wherein the botulinum neurotoxin elutes from the stent.

2. The composition of claim 1 wherein the botulinum neurotoxin is botulinum neurotoxin type A.

3. The composition of claim 1 wherein the botulinum neurotoxin is selected from the group consisting of botulinum neurotoxins A, B, C, D, E, F and G.

4. A self-expanding stent for use in a cardiovascular procedure comprising a therapeutically effective amount of a botulinum neurotoxin attached or embedded therein.

5. An angioplasty balloon for use in a cardiovascular procedure comprising a therapeutically effective amount of a botulinum neurotoxin attached or embedded therein.