Methods and apparatus for cardiac valve repair
The methods, devices, and systems are provided for performing endovascular repair of atrioventricular and other cardiac valves in the heart. Regurgitation of an atrioventricular valve, particularly a mitral valve, can be repaired by modifying a tissue structure selected from the valve leaflets, the valve annulus, the valve chordae, and the papillary muscles. These structures may be modified by suturing, stapling, snaring, or shortening, using interventional tools which are introduced to a heart chamber. Preferably, the tissue structures will be temporarily modified prior to permanent modification. For example, opposed valve leaflets may be temporarily grasped and held into position prior to permanent attachment.
1. A method of modifying a valve in a patient's heart to reduce regurgitation, the valve having an annulus, the method comprising:
advancing a catheter comprising an interventional tool having an anchor deployment mechanism through the patient's vasculature into the heart from a femoral venous location, the anchor deployment mechanism carrying a plurality of deformable anchors;
deploying the plurality of anchors from the anchor deployment mechanism onto the annulus such that each of the deployed anchors penetrates a portion of the tissue of the annulus;
threading a single filament through each of the deployed anchors such that the filament does not penetrate the tissue of the annulus; and
tightening the filament so as to modify the annulus to reduce regurgitation in the valve.
2. The method of claim 1 , wherein the filaments comprise sutures.
3. The method of claim 1 , wherein the anchors comprise staples.
4. The method of claim 1 , wherein advancing the catheter comprises extending the catheter across an inter-atrial septum of the heart.
5. The method of claim 1 , wherein the valve is a mitral valve, and wherein tightening the filament modifies the annulus to reduce regurgitation in the mitral valve.
6. The method of claim 1 , further comprising positioning a guide catheter through the patient's vasculature into the heart from the femoral venous location, and wherein advancing the catheter comprises advancing the catheter through the guide catheter.
7. The method of claim 1 , wherein tightening the filament comprises tightening the annulus.
8. The method of claim 1 , wherein tightening the filament comprises shortening the annulus.
9. The method of claim 1 , wherein tightening the filament comprises circumferentially shortening the annulus.
10. The method of claim 1 , wherein tightening the filament comprises circumferentially tightening the filament by drawing at least some of the anchors together.
11. The method of claim 1 , wherein tightening the filament comprises circumferentially tightening the filament by plicating portions of the annulus.