Nerve stimulation device
View Patent ↗A nerve stimulation device has a pulse generator for generating stimulation pulses and an output for the stimulation pulses from the pulse generator, which is connectable to an electrode arrangement adapted for interaction with a living being to stimulate the phrenic nerve. The nerve stimulation device is made more safe and effective by the provision of an input connectable to an esophageal electrode for the reception of measurement signals. The esophageal electrode is adapted to be inserted in the esophagus of the living being for obtaining measurement signals. A signal analyzer filters myo-electrical signals from the diaphragm out of the measurement signals and a regulating unit regulates the pulse generator dependent on the myo-electrical signals.
1. A nerve stimulation device comprising:
a pulse generator which generates stimulation pulses;
an electrode arrangement connected to the pulse generator configured to interact with a living subject to deliver the stimulation pulses to stimulate the phrenic nerve;
a cardiac signal detector configured to obtain an ECG signal from the living subject indicative of a degree of stimulation of the vagus nerve of the living subject associated with the stimulation of the phrenic nerve by said stimulation pulses; and
a regulating unit connected to said cardiac signal detector and to said pulse generator for regulating the pulse generator dependent on the ECG signal to reduce said degree of stimulation of the vagus nerve by said stimulation pulses.
2. A nerve stimulation device as claimed in claim 1 further comprising a monitoring unit configured to interact with the living subject to monitor breathing of the living subject and which generates a monitoring unit output supplied to said regulating unit, said regulating unit regulating the pulse generator dependent on said monitoring unit output as well as dependent on said ECG signal.
3. A nerve stimulation device as claimed in claim 2 wherein said monitoring unit comprising a breathing detector selected from the group consisting of an external ventilator, a spirometer, an impedance measurement arrangement, a thorax circumference measurement arrangement, and a gas analyzer.
4. A nerve stimulation device as claimed in claim 1 wherein said electrode arrangement comprises a plurality of electrode leads and wherein said pulse generator is connected to said electrode arrangement via an output interface comprising a plurality of channels, with one channel for each electrode lead, and wherein said regulating unit regulates said pulse generator to individually control delivery of stimulation pulses via the respective electrode leads.
5. A nerve stimulation device as claimed in claim 1 wherein said cardiac signal detector comprises:
an esophageal electrode adapted for insertion in the esophagus of the living subject for obtaining measurement signals; and
a signal analyzer connected to the esophageal electrode for filtering said
ECG signal, from said measurement signals.