Full-length human cDNAs encoding potentially secreted proteins
View Patent ↗The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression and/or biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.
1. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 297 or the amino acid sequence of the polypeptide having the internal designation of 181-3-3-0-C9-CS as encoded by a human cDNA in ATCC accession number PTA-1218.
2. The polypeptide of claim 1 , wherein said polypeptide comprises the amino acid sequence of SEQ ID NO: 297.
3. The polypeptide of claim 2 , wherein said polypeptide plays a role in vesicle trafficking.
4. The polypeptide of claim 1 , wherein said polypeptide comprises the amino acid sequence of the polypeptide having the internal designation of 181-3-3-0-C9-CS as encoded by a human cDNA in ATCC accession number PTA-1218.
5. The polypeptide of claim 4 , wherein said polypeptide plays a role in vesicle trafficking.
6. The polypeptide of claim 1 , wherein said polypeptide consists of the amino acid sequence of SEQ ID NO: 297.
7. The polypeptide of claim 6 , wherein said polypeptide plays a role in vesicle trafficking.
8. The polypeptide of claim 1 , where said polypeptide plays a role in vesicle trafficking.
9. A composition comprising an isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 297 or the amino acid sequence of the polypeptide having the internal designation of 181 -3-3-0-C9-CS as encoded by a human cDNA in ATCC accession number PTA-1218.
10. The composition of claim 9 , wherein said polypeptide comprises the amino acid sequence of SEQ ID NO: 297.
11. The composition of claim 10 , wherein said polypeptide plays a role in vesicle trafficking.
12. The composition of claim 9 , wherein said polypeptide comprises the amino acid sequence of the polypeptide having the internal designation of 181-3-3-0-C9-CS as encoded by a human cDNA in ATCC accession number PTA-12 18.
13. The composition of claim 12 , wherein said polypeptide plays a role in vesicle trafficking.
14. The composition of claim 9 , wherein said polypeptide consists of the amino acid sequence of SEQ ID NO: 297.
15. The composition of claim 14 , wherein said polypeptide plays a role in vesicle trafficking.
16. The composition of claim 9 , where said polypeptide plays a role in vesicle trafficking.