IP Library › Granted Patent US 7,220,546
Granted Patent B2
US 7,220,546 · App. 10/658,986 · Granted May 22, 2007

Methods for diagnosing glaucoma and discovering anti-glaucoma drugs

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Quick Facts
Patent No.
US 7,220,546
App. No.
10/658,986
Granted
May 22, 2007
Kind
B2
Abstract

Methods for diagnosing glaucoma and for screening therapeutic agents for their usefulness in treating glaucoma are disclosed.

Claims (4)

1. A method for diagnosing glaucoma in a patient, said method comprising the steps:

(a) obtaining a biological sample from the trabecular meshwork of said patient; and

(b) analyzing said sample for expression of GRβ (SEQ ID NO:1);

wherein a decrease in expression of GRβ as compared to expression of GRβ in a patient not suffering from glaucoma indicates a diagnosis of glaucoma.

Assignments (3)
MERGER Recorded Jul 21, 2008
From: ALCON MANUFACTURING, LTD.
To: ALCON RESEARCH, LTD.
Reel/Frame 021266/0729 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 10, 2003
From: CLARK, ABBOT F.
To: ALCON MANUFACTURING LTD.
Reel/Frame 014501/0183 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 10, 2003
From: WORDINGER, ROBERT J.
To: UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER
Reel/Frame 014504/0853 →