2-phenylbenzimidazole-5-sulphonic acid from isolated 3,4-diaminobenzenesulphonic acid and use thereof in cosmetic preparations
View Patent ↗A process for the preparation of 2-phenylbenzimidazole-5-sulphonic acid, characterized in that 3,4-diaminobenzenesulphonic acid is reacted at a pH between 4 and 7 in aqueous solution with 0.9 to 1.5 mol of benzaldehyde per mole of 3,4-diaminobenzenesulphonic acid and with 1.0 to 3.0 mol of SO 2 per mole of 3,4-diaminobenzenesulphonic acid, or an agent which comprises 1.0 to 3.0 mol of SO 2 per mole of 3.4-diaminobenzenesulphonic acid, is described.
1. Process for the preparation of 2-phenylbenzimidazole-5-sulphonic acid, comprising reacting 3,4-diaminobenzenesulphonic acid at a pH between 4 and 7 in aqueous solution with 0.9 to 1.5 mol of benzaldehyde per mole of 3,4-diaminobenzenesulphonic acid and with 1.0 to 3.0 mol of SO 2 per mole of 3,4-diaminobenzenesulphonic acid, or an agent which comprises 1.0 to 3.0 mol of SO 2 per mole of 3.4-diaminobenzenesulphonic acid, wherein the agent is alkali metal salts selected from the group consisting of Na 2 HSO 3 , Na 2 S 2 O 5 and Na 2 SO 3.
2. Process according to claim 1 , characterized in that 3,4-diaminobenzenesulphonic acid obtained by sulphonation of 1,2-diaminobenzene is used.
3. Process according to claim 1 , characterized in that the reaction is carried out at a pH in the range from 5 to 7.
4. Process according to claim 1 , characterized in that the benzaldehyde is used in an amount of from 1.05 to 1.1 mol/mol.
5. Process according to claim 1 , characterized in that the reaction is carried out at a temperature in the range from 25° to 130° C.
6. 2-phenylbenzimidazole-5-sulphonic acid obtained according to claim 1 which is lightened by means of treatment with an oxidizing agent.