Method of implanting natural tissue within the vertebral disc nucleus space using a drawstring
View Patent ↗Materials and methods for repairing or replacing an intervertebral disc or disc nucleus using natural biological tissue. The tissue may be used alone without an additional core material, or it may be used to encapsulate an elastomeric or hydrogel core. When used alone the tissue may be rolled, folded, braided, or layered to provide a solid plug of natural biological material. When used to encapsulate an elastomeric or hydrogel core the tissue acts as a constraining jacket to support the core. The natural tissue implants may further include a drawstring to assist in folding the implant when the device is implanted in an intervertebral disc space. Multiple units of the natural tissue implants may be used together.
1. A method of augmenting the nucleus of an intervertebral disc, said method comprising the steps of:
(a) implanting in the intervertebral disc an intervertebral disc device comprising a length of natural tissue sized for introduction into an intervertebral disc nucleus space and having a first end and a second end, wherein said length of natural tissue has a first, straightened configuration and a second, folded configuration having a multiplicity of pleated folds wherein said device additionally comprises a drawstring effective for folding said length of natural tissue to its second, folded configuration after implantation of the tissue in a disc nucleus space, said drawstring being secured to the length of natural tissue at or near the first end thereof, said drawstring passing through the tissue from one side thereof to another at a multiplicity of sites at predetermined intervals along the length of the tissue, exiting the tissue at or near the second end thereof and extending beyond said second end to terminate in an end portion for pulling the drawstring;
(b) implanting at least a portion of said length of natural tissue starting with its first end into the disc nucleus space;
(c) pulling the drawstring while holding the second end of the length of natural tissue stationary to cause the folding of the implanted tissue within the disc nucleus space; and,
(d) repeating, if necessary, steps (b) and (c) until the full length of implanted natural tissue has acquired its second, folded configuration within the disc nucleus space.
2. The method of claim 1 wherein said natural tissue comprises a biological tissue or a matrix derived from a biological tissue.
3. The method of claim 1 wherein said natural tissue comprises pericardium tissue.
4. The method of claim 1 wherein said natural tissue comprises small intestine submucosa.
5. The method of claim 1 wherein said drawstring passes though the length of natural tissue at least three sites.
6. The method of claim 1 wherein said drawstring passes through the length of natural tissue at least five sites.
7. the method of claim 1 wherein said drawstring passes through the length of natural tissue at least 10 sites.
8. The method of claim 1 wherein the natural tissue is of braided construction.
9. The method of claim 1 wherein step (b) is carried out with the aid of a cannula.