1,3,5-triazines for treatment of viral diseases
View Patent ↗The present invention provides compounds and methods for treatment of viral diseases and cancer.
1. A compound having the formula:
wherein
R 9 is substituted or unsubstituted acyl;
R 10 is selected from H, and substituted or unsubstituted alkyl;
R 3 is H;
R 4 is H;
R 5 is OH;
R 6 is OH; and
R 8 is H.
2. A formulation of the compound according to claim 1 , and a second compound having the formula:
A-B
wherein
A is a hydrophobic domain; and
B is a hydrophilic domain covalently bound to A.
3. The formulation according to claim 2 , further comprising a polycationic species.
4. The formulation according to claim 3 , wherein said polycationic species is a dendrimeric polyamine.
5. The formulation according to claim 2 , wherein said formulation is an aqueous formulation.
6. The compound according to claim 1 , having the formula:
7. The compound according to claim 1 , wherein R 10 is H.