Subunguicide, and method for treating onychomycosis
View Patent ↗Onychomycosis is a fungal infection of the nail bed and is difficult to treat topically because penetration of the nail plate is difficult, and systemic antifungal treatments are prone to side effects and drug interactions. The present invention treats onychomycosis by applying an antifungal composition to the nail bed directly using a solid, semi-solid, or flowable carrier. The carrier can be in the form of a semi-solid into which the user digs and scrapes the nail, a solid carrier can be inserted directly under the nail in contact with the nail bed, or a flowable composition can be injected in contact with the nail bed.
1. A method for treating onychomycosis, comprising providing a subunguicide including an antifungal agent in a suitable carrier, and administering the same subungually by forcing the subunguicide between the hyponychium and the nail plate and past the hyponychium to be in contact with the nail bed.
2. The method of claim 1 , wherein the subunguicide is placed between the nail plate and the nail bed.
3. The method of claim 1 , wherein the carrier is a solid or a semi-solid.
4. The method of claim 1 , wherein the antifungal agent and carrier subunguicide is provided as a flowable composition selected from gels, creams, lotions, solutions, and suspensions.
5. The method of claim 4 , further comprising:
providing an applicator having a reservoir for holding an amount of the antifungal agent in the suitable carrier and a tube through which the agent and carrier can flow from the reservoir to the end of the tube; placing the tube in contact with the nail bed without penetrating the nail plate; and causing the antifungal agent and carrier to flow through the tube and reside in contact with the nail bed.
6. The method of claim 1 , further comprising the co-administration of a systemic antifungal agent.
7. The method of claim 1 , wherein the carrier is flowable and is administered subungually by high pressure injection.
8. The method of claim 1 , wherein the carrier is flowable and is forced between the nail plate and the hyponychium past the hyponychium to reside in contact with the nail bed.
9. The method of claim 1 , wherein the carrier is solid or semi-solid and is forced between the nail plate and the hyponychium past the hyponychium to reside in contact with the nail bed.