Automated cytological sample classification

1. An automated method of classifying a cytological sample, comprising:

a) obtaining an initial cytological sample from a patient;

b) providing the initial cytological sample in solution in a vessel;

c) optically interrogating the solution containing the initial sample with at least one wavelength of light;

d) determining, based on the interrogation, whether the solution containing the initial sample has an adequate concentration of cellular material;

e) obtaining an additional cytological sample from the patient to be added to the solution if the solution containing the initial sample does not have an adequate concentration of cellular material;

f) attaching a positive designator to the vessel if the solution containing the initial sample has an adequate concentration of cellular material and is satisfactory for preparing a specimen slide; and

g) attaching a manipulation designator to the vessel if the solution containing the initial sample has an adequate concentration of cellular material but requires a manipulation to render the solution containing the initial sample satisfactory for slide preparation.

2. The method of claim 1 , wherein the cellular material comprises prokaryotic, eukaryotic, or archea type cells.

3. The method of claim 1 , wherein the positive designator indicates that the sample is satisfactory for automated slide preparation.

4. The method of claim 1 , wherein the positive designator further indicates that the solution containing the initial sample is adequate in quantity to allow for withdrawal of a portion of the solution containing the initial sample prior to preparing the specimen slide.

5. The method of claim 1 , wherein the manipulation to render the solution containing the initial sample satisfactory for slide preparation comprises adding acetic acid to the solution containing the initial sample.

6. The method of claim 1 , wherein the manipulation to render the solution containing the initial sample satisfactory for slide preparation comprises adding a reducing agent to the solution containing the initial sample.

7. The method of claim 1 , wherein the cellular material is endocervical cells.

8. The method of claim 1 , wherein the solution containing the initial sample requires a manipulation to render the solution containing the initial sample satisfactory for slide preparation if a level of blood or mucus in the solution containing the initial sample exceeds a threshold level of blood or mucus.

9. The method of claim 1 , wherein the positive designator comprises a physical marking on the vessel.

10. The method of claim 1 , wherein the positive designator comprises a designation in an electronic memory.

11. The method of claim 1 , wherein the manipulation designator comprises a physical marking on the vessel.

12. The method of claim 1 , wherein the manipulation designator comprises a designation in an electronic memory.

13. The method of claim 1 , wherein the initial sample is selected from the group consisting of blood; urine; semen; milk; sputum; mucus; plueral fluid; pelvic fluid; sinovial fluid; ascites fluid; a body cavity wash; eye brushing; skin scrapings; a buccal swab; a vaginal swab; a pap smear; a rectal swab; an aspirate; a needle biopsy; a section of tissue; plasma; serum; spinal fluid; lymph fluid; an external secretion of the skin, respiratory, intestinal, or genitourinary tract; tears; saliva; a tumor; an organ; a microbial culture; and an in vitro cell culture constituent.

14. The method of claim 1 , wherein the solution comprises a water-soluble alcohol in an amount effective to preserve the sterility of the initial sample toward at least one contaminant.

15. The method of claim 1 , wherein steps c) and d) occur in temporal conjunction with steps a) and b).

16. The method of claim 1 , wherein step e) occurs in temporal conjunction with steps a) through d).