Novel human genes and proteins encoded thereby
The present invention relates to novel human genes involved in the regulation of signal transduction pathways, and the proteins and polypeptides encoded thereby. In particular, the invention relates to polynucleotides that encode the polypeptides, the polypeptides, antibodies directed to the polypeptides, and methods of diagnosis and treatment of various disorders, including disorders involving the inappropriate regulation of a signal transduction mechanism, for example cancer.
1 .- 20 . (cancelled)
21 . An isolated nucleic acid molecule comprising the nucleotide sequence described in SEQ ID NOS: 1 or 3.
22 . An isolated nucleic acid molecule comprising a nucleotide sequence encoding the amino acid sequence disclosed in SEQ ID NOS: 2 or 4.
23 . A recombinant vector comprising a nucleic acid sequence of claim 24 .
24 . A host cell comprising the recombinant vector of claim 23.