Processes of making North American ginseng fractions, products containing them, and uses as immunomodulators
View Patent ↗The invention is directed to chemical processes of preparing fractions from North American ginseng ( Panax quinquefolium ) and pharmaceutical compositions containing these fractions. The products of the present invention may be used to stimulate the production of cytokines and/or antibodies, or as therapeutics targeted at conditions characterized by low immunity, such as the common cold, influenza, chronic fatigue syndrome, AIDS and cancer.
1. A pharmaceutical compositions, wherein said pharmaceutical composition comprises ginseng fraction CVT-E002 and a pharmaceutically acceptable carrier.
2. A method of preparing a pharmaceutical composition suitable for treating a condition characterized by low immunity, wherein said method comprises combining an effective amount of ginseng fraction CVT-E002 and, optionally, an effective amount of another medicament that is suitable for treating a condition characterized by low immunity with at least one pharmaceutically acceptable excipient to produce a pharmaceutical composition suitable for treating a condition characterized by low immunity.
3. The method of claim 2 , wherein the condition is selected from the group consisting of common cold, influenza, chronic fatigue syndrome, AIDS and cancer.
4. A method of stimulating the production of IL-1, IL-6 and/or TNF-α in cells, wherein said method comprises contacting said cells with an effective amount of ginseng fraction CVT-E002.
5. A method of activating B-lymphocyte proliferation and antibody production resulting from said B-lymphocyte proliferation in a patient in need of such proliferation, wherein said method comprises administering to the patient an effective amount of ginseng fraction CVT-E002.
6. A method of treating a condition characterized by low immunity in a patient in need thereof, comprising administering to the patient an effective amount of ginseng fraction CVT-E002.
7. The method of claim 6 , wherein the condition is selected from the group consisting of common cold, influenza, chronic fatigue syndrome, AIDS and cancer.
8. A method of stimulating the in vitro production of immunoglobulins in cells, wherein said method comprises contacting cells with an effective amount of ginseng fraction CVT-E002.
9. A method of stimulating the in vivo production of immunoglobulins in a subject in need thereof, wherein said method comprises administering to the subject an effective amount of ginseng fraction CVT-E002.