Protein having ribonucleotide reductase activity and DNA thereof
View Patent ↗A protein having ribonucleotide reductase activity, DNA encoding the protein, antibodies to these and the like are disclosed. The protein, DNA and antibodies are useful in the prevention, treatment and diagnosis, etc. of cancer.
1. An isolated nucleic acid molecule comprising a base sequence encoding a protein having the amino acid sequence set forth as SEQ ID NO: 1 and having ribonucleotide reductase activity.
2. The isolated nucleic acid molecule according to claim 1 , wherein the molecule is DNA.
3. The isolated nucleic acid molecule according to claim 2 , wherein the molecule comprises the base sequence set forth as SEQ ID NO: 2.
4. The isolated nucleic acid molecule according to claim 2 , wherein the molecule comprises the base sequence set forth as SEQ ID NO: 12.
5. A recombinant vector comprising the nucleic acid molecule according to claim 1 .
6. A pharmaceutical composition comprising the nucleic acid molecule according to claim 1 and a pharmaceutically acceptable carier.