IP Library Patent Application 10702096
Patent Application
App. No. 10/702,096

Semi-biological intervertebral disc replacement system

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Patent No.
US None
App. No.
10/702,096
Abstract

The present invention is a system for a partially biological disc replacement that stimulates natural fibrous, cartilaginous or other tissue growth in the DDD cavity, resulting in a partial biological disc replacement. Multiplicities of fibronous pieces of fibro-cartilaginous tissue promoting material are inserted into the DDD cavity inducing tissue growth. The fibro-cartilaginous tissue

Claims (77)

1 . A system for semi-biologic nuclear replacement for a degenerated disc of a spine of a mammalian body comprising:

an injection tube having a small diameter corresponding to a small entrance hole defined in the degenerated disc that is at least partially excavated to create a cavity;

a volume of tissue promoting material sufficient to fill at least a portion of the cavity; and

an insertion device operably coupled to the injection tube that dispenses the volume of tissue promoting material into the cavity in a piecemeal manner as a plurality of aliquots of the tissue promoting material.

2 . The nuclear replacement of claim 1 wherein the tissue promoting material is selected from a group consisting of fibrous tissue promoting material, cartilaginous promoting material and any combination thereof.

3 . The nuclear replacement of claim 1 wherein the tissue promoting material is a preparation of multilayered bands piled in a circular configuration.

4 . The nuclear replacement of claim 1 wherein the tissue promoting material is a preparation of tangled knots.

5 . The nuclear replacement of claim 1 wherein the tissue promoting material is a preparation of multiple fabric bands.

6 . The nuclear replacement of claim 1 wherein the tissue promoting material is combined with hydrogel.

7 . The nuclear replacement of claim 1 wherein the tissue promoting material is surrounded by a porous container.

8 . The nuclear replacement of claim 1 wherein the tissue promoting material is selected from a group consisting of: autograft, allograft, or xenograft of fascia, manmade polymeric fiber, talc, tissue promoting pharmaceuticals, tissue promoting minerals, tissue morphogenic protein, notochord cells and any combination thereof.

9 . A system for semi-biologic nuclear replacement for a degenerated disc of a spine of a mammalian body comprising:

an injection tube having a small diameter corresponding to a small entrance hole defined in the degenerated disc that is at least partially excavated to create a cavity;

a volume of strands of tissue promoting material combined with hydrogel strands sufficient to fill at least a portion of the cavity; and

an insertion device operably coupled to the injection tube that dispenses the volume of strands of tissue promoting material combined with strands of hydrogel into the cavity in a piecemeal manner as a plurality of aliquots of the tissue promoting material and hydrogel strands.

10 . The nuclear replacement of claim 9 wherein the tissue promoting material is selected from a group consisting of fibrous tissue promoting material, cartilaginous promoting material and any combination thereof.

11 . The nuclear replacement of claim 9 wherein the tissue promoting material is a preparation of multilayered bands piled in a circular configuration.

12 . The nuclear replacement of claim 9 wherein the tissue promoting material is a preparation of tangled knots.

13 . The nuclear replacement of claim 9 wherein the tissue promoting material is a preparation of multiple fabric bands.

14 . The nuclear replacement of claim 9 wherein the tissue promoting material is surrounded by a porous container.

15 . The nuclear replacement of claim 9 wherein the tissue promoting material is selected from a group comprising: autograft, allograft, or xenograft of fascia, autograft, manmade polymeric fiber, talc, tissue promoting pharmaceuticals, tissue promoting minerals, tissue morphogenic protein, notochord cells and any combination thereof.

16 . A system for semi-biologic nuclear replacement for a degenerated disc of a spine of a mammalian body comprising:

an injection tube having a small diameter corresponding to a small entrance hole defined in the degenerated disc that is at least partially excavated to create a cavity;

at least one strand of pliable tissue promoting material having an effective cross-sectional diameter less than the small diameter of the injection tube;

the at least one strand of pliable tissue promoting material having a volume sufficient to fill at least a portion of the cavity; and

an insertion device operably coupled to the injection tube that dispenses a length of the pliable tissue promoting material into the cavity such that the at least one strand is folded so as to fill at least a portion of the cavity.

17 . The nuclear replacement of claim 1 wherein the tissue promoting material is selected from a group consisting of fibrous tissue promoting material, cartilaginous promoting material and any combination thereof.

18 . The nuclear replacement of claim 16 wherein the tissue promoting material is a preparation of multilayered bands piled in a circular configuration.

19 . The nuclear replacement of claim 16 wherein the tissue promoting material is a preparation of tangled knots.

20 . The nuclear replacement of claim 16 wherein the tissue promoting material is a preparation of multiple fabric bands.

21 . The nuclear replacement of claim 16 wherein the tissue promoting material is combined with hydrogel.

22 . The nuclear replacement of claim 16 wherein the tissue promoting material is surrounded by a porous container.

23 . The nuclear replacement of claim 16 wherein the tissue promoting material is selected from a group comprising: autograft, allograft, or xenograft of fascia, autograft, manmade polymeric fiber, talc, tissue promoting pharmaceuticals, tissue promoting minerals, tissue morphogenic protein, notochord cells and any combination thereof.

24 . A method of constructing a semi-biologic nuclear replacement for a degenerated disc of a spine of a mammalian body comprising:

boring a small entrance hole into the degenerated disc;

creating a cavity by reaming the degenerated disc and at least partially removing a degenerated disc nucleus via the small entrance hole; and

inserting a plurality of pieces of tissue promoting material into the cavity to create the semi-biologic nuclear replacement for the degenerated disc by stimulating the tissue forming response in the mammalian body to the tissue promoting material.

25 . The method of claim 24 wherein the tissue promoting material is selected from a group consisting of fibrous tissue promoting material, cartilaginous promoting material and any combination thereof.

26 . The method of claim 24 wherein endplate cartilage is partially removed.

27 . The method of claim 24 wherein endplate cartilage is retained.

28 . The method of claim 24 wherein portions of an outer annulus are removed.

29 . The method of claim 24 wherein portions of an outer annulus are retained.

30 . The method of claim 24 wherein the tissue promoting material is selected from a group comprising: autograft, allograft, or xenograft of fascia, manmade polymeric fiber, talc, tissue promoting pharmaceuticals, tissue promoting minerals, tissue morphogenic protein, notochord cells and any combination thereof.

31 . The method of claim 24 wherein the disc cavity surface is coated with a tissue promoting material.

32 . The method of claim 24 wherein the tissue promoting material is combined with hydrogel.

33 . The method of claim 24 further comprising:

inserting a porous container into the disc cavity;

said porous container adapted for tissue promoting material insertion therein.

34 . A method of constructing a semi-biologic nuclear replacement for a degenerated disc of a spine of a mammalian body comprising:

boring a small entrance hole into the degenerated disc;

creating a cavity by reaming the degenerated disc and at least partially removing a degenerated disc nucleus via the small entrance hole; and

inserting at least one strand of pliable tissue promoting material into the cavity such that a length of the at least one strand is folded within the cavity to create the semi-biologic nuclear replacement for the degenerated disc by stimulating the tissue forming response in the mammalian body to the tissue promoting material.

35 . The method of claim 34 wherein the tissue promoting material is selected from a group consisting of fibrous tissue promoting material, cartilaginous promoting material and any combination thereof.

36 . The method of claim 34 wherein endplate cartilage is partially removed.

37 . The method of claim 34 wherein the endplate cartilage is retained.

38 . The method of claim 34 wherein portions of an outer annulus are removed.

39 . The method of claim 34 wherein an outer annulus is retained.

40 . The method of claim 34 wherein the tissue promoting material is selected from a group consisting of: autograft, allograft, or xenograft of fascia lata, autograft, manmade polymeric fiber, talc, tissue promoting pharmaceuticals, tissue promoting minerals, tissue morphogenic protein, notochord cells, and any combination thereof.

41 . The method of claim 34 wherein the disc cavity surface is coated with a tissue promoting material.

42 . The method of claim 34 wherein the tissue promoting material is combined with hydrogel.

43 . The method of claim 34 further comprising:

inserting a porous container into the disc cavity;

said porous container adpapted for tissue promoting material insertion therein.

44 . A method of constructing a semi-biologic nuclear replacement for a degenerated disc of a spine of a mammalian body comprising:

boring a small entrance hole into the degenerated disc;

creating a cavity by reaming the degenerated disc and at least partially removing a degenerated disc nucleus via the small entrance hole; and

inserting a plurality of pieces of tissue promoting material combined with a plurality of pieces of hydrogel into the cavity to create the semi-biologic nuclear replacement for the degenerated disc by stimulating the tissue forming response in the mammalian body to the tissue promoting material and hydrogel.

45 . The nuclear replacement of claim 44 wherein the tissue promoting material is selected from a group consisting of fibrous tissue promoting material, cartilaginous promoting material and any combination thereof.

46 . The method of claim 44 wherein endplate cartilage is partially removed.

47 . The method of claim 44 wherein the endplate cartilage is retained.

48 . The method of claim 44 wherein portions of an outer annulus are removed.

49 . The method of claim 44 wherein an outer annulus is retained.

50 . The method of claim 44 wherein the tissue promoting material is selected from a group consisting of: autograft, allograft, or xenograft of fascia lata, autograft, manmade polymeric fiber, talc, tissue promoting pharmaceuticals, tissue promoting minerals, tissue morphogenic protein, notochord cells, and any combination thereof.

51 . The method of claim 44 wherein the disc cavity surface is coated with a tissue promoting material.

52 . The method of claim 44 further comprising:

inserting a porous container into the disc cavity;

said porous container adapted for tissue promoting material insertion therein.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Mar 5, 2012
From: MUSCULOSKELETAL TRANSPLANT FOUNDATION, INC.
To: SPINEOLOGY, INC.
Reel/Frame 027805/0445 →
SECURITY AGREEMENT Recorded Nov 30, 2006
From: SPINEOLOGY, INC.
To: MUSCULOSKELETAL TRANSPLANT FOUNDATION, INC.
Reel/Frame 018563/0350 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 19, 2004
From: KUSLICH, STEPHEN D.
To: SPINEOLOGY, INC.
Reel/Frame 015112/0916 →