IP Library › Granted Patent US 7,416,546
Granted Patent B2
US 7,416,546 · App. 10/706,965 · Granted Aug 26, 2008

Tissue patches and related delivery systems and methods

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Quick Facts
Patent No.
US 7,416,546
App. No.
10/706,965
Granted
Aug 26, 2008
Kind
B2
Abstract

Endoluminally delivered tissue patches and related systems and methods for delivering the tissue patches for treating lesions of the alimentary tract are disclosed. A tissue patch includes a substrate, a tissue implant attached to the substrate, and a protective liner covering at least a portion of the tissue implant. A method includes providing a tissue patch having a tissue implant attached to a substrate and a protective liner covering at least a portion of the tissue implant. The tissue patch is formed into a contracted state and inserted into a lumen containing the lesion. The tissue patch then is positioned in the vicinity of the lesion. After removing the protective liner to reveal the tissue implant, the tissue implant is placed in the lesion.

Claims (19)

1. A method of treating a lesion in a nonvascular lumen of patient's body, comprising:

providing a tissue patch having a tissue implant attached to a substrate and a protective liner covering at least a portion of the tissue implant;

forming the tissue patch into a contracted state;

inserting the tissue patch in the contracted state into a lumen containing the lesion;

positioning the tissue patch in the vicinity of the lesion;

removing the protective liner to reveal the tissue implant;

and placing the tissue implant in the lesion.

2. A method according to claim 1 , further comprising placing the tissue patch on a portion of a catheter for inserting the tissue patch in the contracted state.

3. A method according to claim 1 , further comprising expanding the tissue patch from the contracted state before the step of removing the protective liner.

4. A method according to claim 1 , wherein an adhesive material is provided on the substrate and the protective liner attaches to the adhesive material.

5. A method according to claim 1 , wherein at least a portion of the substrate includes an adhesive material.

6. A method according to claim 1 , wherein the tissue implant is placed on a surface of the substrate.

7. A method according to claim 1 , wherein the tissue implant is embedded in the substrate in a form of a cellular suspension.

8. A method according to claim 1 , wherein the substrate is a bio-absorbable gel.

9. A method according to claim 1 , further comprising attaching a carrier to the substrate on a surface opposite to the surface facing the lesion and removing the carrier from the substrate after the tissue implant is placed in the lesion.

10. A method according to claim 1 , wherein the tissue implant is an engineered tissue.

11. A method according to claim 1 , wherein forming the tissue patch into a contracted state includes folding the tissue patch.

12. A method according to claim 1 , wherein forming the tissue patch into a contracted state includes rolling the tissue patch into a cylindrical shape.

13. A method according to claim 1 , wherein the implant of tissue comprises a sheet of tissue.

Assignments (1)
CHANGE OF NAME Recorded Nov 6, 2006
From: SCIMED LIFE SYSTEMS, INC.
To: BOSTON SCIENTIFIC SCIMED, INC.
Reel/Frame 018505/0868 →