Hydrogen peroxide disinfectant containing a cyclic carboxylic acid and/or aromatic alcohol
View Patent ↗An aqueous disinfecting solution and dry powdered composition which may be dissolved in water to provide the solution. The solution has a pH of from 0.6 to 7 and comprises (a) hydrogen peroxide in a concentration of from 0.01 to 6% w/w; and (b) at least one component chosen from cyclic carboxylic acids and aromatic alcohols, in a concentration of from 0.01 to 4 w/w %, all based on the total weight of the solution. The cyclic carboxylic acids are preferably 2-furan carboxylic acid, benzoic acid and salicylic acid. Furthermore, the solution preferably contains at least one C6-C12 alkyl diphenyl oxide sulfonate surfactant and a nonionic surfactant. Additional optional ingredients include anionic surfactants, corrosion inhibitors, cation sequestering agents, and buffers.
1. An aqueous solution effective in killing mycobacteria and spores, having a pH of from 0.6 to 7 and comprising:
(a) hydrogen peroxide in a concentration of from 0.01 to 6% w/w, based on the total weight of the solution; and
(b) 2-furan carboxylic acid in a concentration of from 0.01 to 8% w/w, based on the total weight of the solution.
2. A solution according to claim 1 wherein said 2-furan carboxylic acid is present in a concentration of from 0.1 to 4% w/w, based on the total weight of the solution.
3. A solution according to claim 2 wherein said 2-furan carboxylic acid is present in a concentration of from 0.1 to 2.5% w/w, based on the total weight of the solution.
4. A solution according to claim 1 further comprising benzyl alcohol.
5. A solution according to claim 4 further comprising benzoic acid.
6. A solution according to claim 4 further comprising salicylic acid.
7. A solution according to claim 1 further comprising at least one nonionic surfactant in a concentration of from 0.005 to 3% w/w, based on the total weight of the solution.
8. A solution according to claim 7 wherein said at least one nonionic surfactant is present in a concentration of from 0.01 to 3% w/w, based on the total weight of the solution.
9. A solution according to claim 8 wherein said at least one nonionic surfactant is present in a concentration of from 0.01 to 1% w/w, based on the total weight of the solution.
10. A solution according to claim 7 wherein said at least one nonionic surfactant is chosen from (a) ethoxylated alcohols and alkylglycosides having a hydrophile lyophile balance from 5 to 15; and (b) a sufficiently water-soluble block copolymer of ethylene oxide or propylene oxide.
11. A solution according to claim 10 wherein said at least one nonionic surfactant is a sufficiently water-soluble block copolymer of ethylene oxide or propylene oxide, a C6-C10 alkyl, 3.5 moles of ethylene oxide (EO) alcohol ethoxylate, or a combination thereof.
12. A solution according to claim 1 further comprising at least one cation sequestering agent in a concentration of from 0.01 to 6% w/w, based on the total weight of the solution.
13. A solution according to claim 12 wherein said cationic sequestering agent is present in a concentration of from 0.05 to 2% w/w, based on the total weight of the solution.
14. A solution according to claim 12 wherein said cation sequestering agent is 1-hydroxyethylidene-1,1-diphosphonic acid.
15. A solution according to claim 1 further comprising at least one anionic surfactant chosen from (a) C8-C16 alkyl benzene sulfonic acids and alkali metal, alkaline earth metal, ammonium or alkylamine salts thereof (b) C8-C18 alkyl sulfonic acids; (c) C8-C16 alkyl sulfates; and (d) C6-C12 alkyl diphenyl oxide sulfonate in a concentration of from 0.01 to 10% w/w, based on the total weight of the solution.
16. A solution according to claim 15 wherein said at least one anionic surfactant is present in a concentration of from 0.01 to 6% w/w, based on the total weight of the solution.
17. A solution according to claim 16 wherein said at least one anionic surfactant is present in a concentration of from 0.05 to 3% w/w, based on the total weight of the solution.
18. A solution according to claim 15 wherein said at least one anionic surfactant is chosen from alkyl benzene sulfonic acids and C6-C10 alkyl diphenyl oxide sulfonates.
19. A solution according to claim 15 wherein said at least one anionic surfactant is chosen from a C6 alkylated sulfonated diphenyl oxide sodium salt, a C10 alkylated sulfonated diphenyl oxide sodium salt, and dodecyl benzene sulfonic acid.
20. A solution according to claim 1 having a pH of from 0.6 to 5.
21. A solution according to claim 20 having a pH of from 2 to 4.
22. A solution according to claim 1 further comprising at least one buffer in an amount effective to buffer the solution to said pH.
23. A solution according to claim 22 wherein said at least one buffer is chosen from phosphoric acid, citric acid, glycolic acid, sodium carbonate, calcium carbonate, potassium hydroxide, sodium hydroxide, ethanolamine and lactic acid.
24. A solution according to claim 1 further comprising at least one corrosion inhibitor in a concentration of from 0.001 to 15% w/w, based on the total weight of the solution.
25. A solution according to claim 24 wherein the at least one corrosion inhibitor is present in a concentration of from 0.01 to 5% w/w, based on the total weight of the solution.
26. A solution according to claim 25 wherein the at least one corrosion inhibitor is present in a concentration of from 0.01 to 1% w/w, based on the total weight of the solution.
27. A solution according to claim 24 wherein the at least one corrosion inhibitor is chosen from 1,2,3 benzotriazole, sodium molybdate, sodium nitrite, sodium bisulfate, sodium metabisulfate, chromates, borates, phosphates, polyphosphates, sodium benzoate, sodium gluconate and sodium silicate.
28. A solution according to claim 1 wherein said hydrogen peroxide is present in a concentration of from 0.25 to 4% w/w, based on the total weight of the solution.
29. A solution according to claim 1 further comprising a hydrotrope in a concentration of from 0.01 to 15% w/w, based on the total weight of the solution.
30. A solution according to claim 29 wherein said hydrotrope is sodium xylene sulfonate.
31. A solution according to claim 1 further comprising a solvent in a concentration of from 0.01 to 15% w/w, based on the total weight of the solution.
32. A solution according to claim 31 wherein said solvent is a glycol or glycol ether.
33. A solution according to claim 1 further comprising benzoic acid.
34. A solution according to claim 1 further comprising salicylic acid.
35. A concentrated, aqueous, acidic disinfecting solution which may be diluted with water to provide a solution according to claim 1 .
36. A solution according to claim 35 wherein the 2-furan carboxylic acid is present in a concentration up to 30% w/w, based on the total weight of the solution.
37. A multi-component system which can be combined to provide a disinfecting solution according to claim 1 .
38. A method of disinfecting equipment in place comprising the steps of
(a) providing a solution according to claim 1 ; and
(b) circulating said solution in place through said equipment at a temperature of from 20 to 60 degrees Celsius to disinfect the equipment.
39. A method of disinfecting a surface comprising the step of applying a solution according to claim 1 to the surface to disinfect the surface.