IP Library Granted Patent US 6,939,885
Granted Patent B2
US 6,939,885 · App. 10/716,170 · Granted Sep 6, 2005

Aryl sulfonamides

Assignee: Chemocentryx
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Quick Facts
Patent No.
US 6,939,885
App. No.
10/716,170
Granted
Sep 6, 2005
Kind
B2
Abstract

Compounds are provided that act as potent antagonists of the CCR9 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.

Claims (6)

1. A compound of the formula (I):

or a salt thereof.

2. The compound of claim 1 wherein the salt of the compound is selected from the group consisting of aluminum, ammonium, calcium, copper, ferric, ferrous, lithium, magnesium, manganic, manganous, potassium, sodium, or zinc.

3. A composition comprising a pharmaceutically acceptable carrier and a compound of the formula (I):

or a salt thereof.

4. The composition of claim 3 wherein the salt of the compound is selected from the group consisting of aluminum, ammonium, calcium, copper, ferric, ferrous, lithium, magnesium, manganic, manganous, potassium, sodium, or zinc.

Assignments (5)
ASSIGNEE CHANGE OF ADDRESS Recorded Jun 27, 2023
From: CHEMOCENTRYX, INC.
To: CHEMOCENTRYX, INC.
Reel/Frame 064144/0685 →
CORRECT THE FIRST AND THIRD ASSIGNOR NAMES, AND RECORD A CHANGE OF ADDRESS OF THE ASSIGNEE ON REEL/FRAME 015252/0240 Recorded Sep 15, 2005
From: UNGASHE, SOLOMON; WEI, ZHENG; WRIGHT, JOHN J.; PENNELL, ANDREW
To: CHEMO CENTRYX, INC.
Reel/Frame 016804/0506 →
TO CORRECT THE FIRST AND THIRD ASSIGNOR NAME AND RECORD A CHANGE OF ADDRESS OF THE ASSIGNEE ON ASSIGNMENT DOCUMENT PER RECORDED ON REEL/FRAME 015252/0240. Recorded Jul 8, 2005
From: UNGASHE, SOLOMON; WEI, ZHENG; WRIGHT, JOHN J.; PENNELL, ANDREW
To: CHEMOCENTRYX, INC.
Reel/Frame 016496/0720 →
CORRECTIVE ASSIGNMENT TO CORRECT THE FIRST AND THIRD NAMES OF THE CONVEYING PARTY, ALONG WITH THE ADDRESS OF THE ASSIGNEE PREVIOUSLY RECORDED AT REEL 015252 FRAME 0240. THE CONVEYING PARTYS' HEREBY CONFIRM THE ASSIGNMENT OF THE ASSIGNEE. Recorded Jul 8, 2005
From: UNGASHE, SOLOMON; WEI, ZHENG; WRIGHT, JOHN J.; PENNELL, ANDREW
To: CHEMOCENTRYX, INC.
Reel/Frame 016848/0218 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 22, 2004
From: UGASHE, SOLOMON; WEI, ZHENG; WRIGHT, J.J.; PENNELL, ANDREW
To: CHEMOCENTRYX
Reel/Frame 015252/0240 →
Continuity (2)
Provisional Application 6042767000 · Nov 18, 2002
Related Publication 20040171654A1 · Sep 2, 2004