Agent for improving acidosis
View Patent ↗An agent for improving ketosis which comprises an insulin sensitizer, which has an excellent action and low toxicity.
1. A method of treating acidosis in a mammal in need thereof which comprises administering to said mammal an effective amount of an insulin sensitizer in combination with insulin, wherein the insulin sensitizer is selected from pioglitazone or a salt thereof;
wherein said acidosis is acidosis caused by metformin.
2. A method of treating acidosis in a mammal in need thereof, which comprises administering to said mammal an effective amount of an insulin sensitizer selected from pioglitazone or a salt thereof;
wherein said acidosis is acidosis caused by metformin.
3. The method of claim 1 wherein the insulin sensitizer is pioglitazone hydrochloride.
4. The method of claim 2 wherein the insulin sensitizer is pioglitazone hydrochloride.
5. A method of treating acidosis in a mammal in need thereof which comprises administering to said mammal an effective amount of an insulin sensitizer in combination with insulin;
wherein:
the insulin sensitizer is selected from pioglitazone or a salt thereof;
said acidosis is diabetic acidosis; and
said mammal has type II diabetes.
6. A method of treating acidosis in a mammal in need thereof, which comprises administering to said mammal an effective amount of an insulin sensitizer selected from pioglitazone or a salt thereof;
wherein:
said acidosis is diabetic acidosis; and
said mammal has type II diabetes.