Lens care composition and method
View Patent ↗An buffered aqueous contact lens disinfecting solution having much lower concentration of disinfecting agents, and less irritating to the eye. The solutions have a tonicity of 200 to 450 mOsm/kg, a pH of between 6 and 8, and a concentration of chloride ions below 1500 ppm. Despite having less than 1 ppm of antimicrobial, the solutions are effective against C. albicans within 15 minutes of contact.
1. An aqueous contact lens disinfecting solution, comprising:
(a) less than 0.5 ppm PHMB;
(b) 0.01% to 0.1% dexpanthenol;
(c) 0.001% to 0.5% polyoxyethylene-polyoxypropylene block polymer;
(d) 0.001% to 0.5% ethoxylated glucose derivative;
(e) bis-TRIS-propane buffer;
(f) 0.1% to 0.3% viscosity enhancing agent;
(g) less than 0.2% chelating agent; and
(h) at least 4% of a tonicity agent selected from the group consisting of glycerol, urea, propylene glycol, sodium bicarbonate, sugars, alcohols, polyols, and mixtures thereof; wherein said solution has a tonicity of 200 to 450 mOsm/kg, a pH of between 6 and 8, and a concentration of chloride ions below 500 ppm; and wherein said solution will result in at least a 1 log reduction in C. albicans within 15 minutes of contact.
2. An aqueous contact lens disinfecting solution as claimed in claim 1 , wherein said chelating agent is EDTA; said viscosity enhancing agent is PVP; and said tonicity agent is sorbitol.
3. An aqueous contact lens disinfecting solution as claimed in claim 1 , wherein said viscosity enhancing agent is PVP.
4. An aqueous contact lens disinfecting solution as claimed in claim 1 , wherein said tonicity agent is sorbitol.
5. An aqueous contact lens disinfecting solution as claimed in claim 1 , wherein said chelating agent is EDTA.