IP Library Granted Patent US 8,187,612
Granted Patent B2
US 8,187,612 · App. 10/726,904 · Granted May 29, 2012

Use of the neurotoxic component of a botulinum toxin for treating a spastic muscle

Assignee: Allergan, Inc.
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Quick Facts
Patent No.
US 8,187,612
App. No.
10/726,904
Granted
May 29, 2012
Kind
B2
Abstract

A method and composition for treating a patient suffering from a disease, disorder or condition and associated pain include the administration to the patient of a therapeutically effective amount of a neurotoxin selected from a group consisting of botulinum toxin types A, B, C, D, E, F and G.

Claims (6)

1. A method for treating strabismus, wherein said method is a human medical application and comprises the step of administering to a human patient a therapeutically effective amount of a neurotoxic component of a botulinum toxin type B to thereby treat strabismus wherein the neurotoxic component administered to the human patient has a molecular weight of about 150 kilodaltons, wherein the neurotoxic component is administered by intramuscular injection or by subcutaneous injection, and wherein the administration of the neurotoxic component results in alleviation of the strabismus within 1 day to 7 days.

2. The method of claim 1 , wherein between about 0.01 units and about 500 units of the neurotoxic component is administered.

3. The method of claim 1 , wherein between about 80 units and about 460 units of the neurotoxic component is administered.

4. A method for treating strabismus, the method comprising the step of administering to a human patient a therapeutically effective amount of a neurotoxic component of botulinum toxin type B to treat strabismus, wherein the neurotoxic component is administered by intramuscular injection or by subcutaneous injection, and the administration of the neurotoxic component results in alleviation of the strabismus within 1 day to 7 days.

5. The method of claim 4 , wherein between about 0.01 units and about 500 units of the neurotoxic component is administered.

6. The method of claim 4 , wherein between about 80 units and about 460 units of the neurotoxic component is administered.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 17, 2007
From: MERZ PHARMA GMBH & CO. KGAA; MERZ PHARMACEUTICALS GMBH
To: ALLERGAN, INC.
Reel/Frame 019831/0865 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 2, 2003
From: AOKI, KEI ROGER; GRAYSTON, MICHAEL W.; CARLSON, STEVEN R.; LEON, JUDITH M.
To: ALLERGAN, INC.
Reel/Frame 014777/0091 →
Continuity (3)
Continuation In Part 08627118 · Apr 3, 1996
Continuation 08173996 · Dec 28, 1993
Related Publication 20040126397A1 · Jul 1, 2004