Prepolymers for improved surface modification of contact lenses
View Patent ↗Provided are novel reactive functionalized fumaric- and itaconic-containing prepolymers and compositions comprising the prepolymers used in the manufacture of medical devices. The prepolymers can be used to provide surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having reactive functionality that is complimentary to reactive, hydrophilic polymers.
1. A prepolymer selected from the group consisting of functionalized compounds having the following formula:
YCO—CH═CHCOW(R 1 ) n (SiR 2 R 3 O) m (SiR 2 R 3 )(R 1 ) n WOCCH═CH—COY
and
CH 2 ═C(CH 2 COY)COW(R 1 ) n (SiR 2 R 3 O) m (SiR 2 R 3 )(R 1 ) n WOC(CH 2 COY)C═CH 2
wherein R 1 is selected from the group consisting of alkylenes and alkylenes containing ether linkages, R 2 and R 3 are independently selected from the group consisting of alkyl groups, phenyl groups, alkyl groups substituted with halcgen, phenyl groups substituted with halogen, alkyl groups containing ether linkages and phenyl groups containing ether linkages, W is O or NH, n is an integer between 1 and 10, m is an integer between 2 and 200, and Y is a residue having a reactive functional group selected from the group consisting of oxazolone, epoxy and anhydride functional groups with the proviso that when W is O, Y is not a residue of diethanglamine.
2. The prepolymer of claim 1 wherein R 1 contains 1–10 carbon atoms.