High strength suture with absorbable core
View Patent ↗A novel high tensile strength semi-absorbable composite suture with minimized non-absorbable mass. The suture has a core made from a bioabsorbable polymer. The core is covered by a braided sheath. The braided sheath is made from an absorbable yarn and a bioabsorbable yarn. The bioabsorbable yarn is made from a least one filament of a bioabsorbable polymer. The nonabsorbable yarn is made from at least one filament of ultra high molecular weight polyethylene.
1. A surgical suture, comprising:
an inner core comprising at least one yarn comprised of at least one fiber, said fiber comprising a bioabsorbable polymer; and,
an outer braided sheath comprising a second yarn comprised of at least one nonabsorbable fiber and a third yarn comprising at least one bioabsorbable fiber, wherein the second and third yarns are in intertwining contact, and wherein the bioabsorbable first and bioabsorbable third yarns comprise a polymer prepared from lactone monomers selected from the group consisting of p-dioxanone, ε-caprolactone, glycolide, L(−)-lactide, D(+)-lactide, meso-lactide, trimethylene carbonate, and combinations thereof, and wherein the nonabsorbable fiber comprises ultra high molecular weight polyethylene, and wherein the suture comprises about 55 wt. % to about 70 wt. % of bioabsorbable polymer.
2. The suture of claim 1 , wherein the bioabsorbable yarns comprise polydioxanone.
3. The suture of claim 1 , wherein the bioabsorbable first and second yarns comprise a pharmaceutical composition.
4. The suture of claim 3 wherein the first and second yarns comprise a pharmaceutical composition selected from the group consisting of analgesics, antibiotics, anti-inflammatories, and pain killers.
5. The suture of claim 1 wherein the polyethylene yarn comprises an ultra high molecular weight polyethylene having a weight average molecular weight of about 500,000 to about 5,000,000 g/mole.
6. The suture of claim 1 , additionally comprising a coating.
7. The suture of claim 1 additionally comprising a surgical needle mounted to one end.
8. A method of approximating tissue, comprising:
providing a suture, said suture comprising:
an inner core comprising at least one yarn comprised of at least one fiber, said fiber comprising a bioabsorbable polymer; and,
an outer braided sheath comprising a second yarn comprised of at least one nonabsorbable fiber and a third yarn comprising at least one bioabsorbable fiber, wherein the second and third yarns are in intertwining contact,
and wherein the bioabsorbable first and bioabsorbable third yarns comprise a polymer prepared from lactone monomers selected from the group consisting of p-dioxanone, ε-caprolactone, glycolide, L(−)-lactide, D(+)-lactide, meso-lactide, trimethylene carbonate, and combinations thereof, and wherein the nonabsorbable fiber comprises ultra high molecular weight polyethylene, and wherein the suture comprises about 55 wt. % to about 70 wt. % of bioabsorbable polymer,
stitching said suture through tissue; and,
tying a knot in the suture.
9. The method of claim 8 , wherein the yarns comprises polydioxanone.
10. The method of claim 8 , wherein the bioabsorbable first and second yarns comprise a pharmaceutical composition.
11. The method of claim 10 wherein the first and second yarns comprise a pharmaceutical composition selected from the group consisting of analgesics, antibiotics, anti-inflammatories, and pain killers.
12. The method of claim 8 wherein the polyethylene yarn comprises an ultra high molecular weight polyethylene having a molecular weight of about 500,000 to about 5,000,000 g/mole.
13. The method of claim 8 , additionally comprising a coating on the suture.
14. The method of claim 8 additionally comprising a surgical needle mounted to one end of the suture.
15. The suture of claim 1 , wherein the first and second yarns additionally comprise a bioceramic material.
16. The suture of claim 1 , wherein the first and second yarns comprise a material selected from the group consisting of tricalcium phosphate and hydroxyapatite.
17. The method of claim 8 , wherein the first and second yarns additionally comprise a bioceramic material.
18. The method of claim 8 , wherein the first and second yarns comprise a material selected from the group consisting of tricalcium phosphate and hydroxyapatite.
19. The suture of claim 2 wherein the yarn comprises a filament having a denier greater than 3 denier per filament.
20. The suture of claim 2 wherein the yarn comprises a filament having a denier greater than 12 denier per filament without substantial adverse effect to suture handling and stiffness when compared to the commercially available sutures prepared from ultra high molecular weight polyethylene/PET.
21. The suture of claim 2 wherein the yarn comprises a filament having a denier greater than 12 denier per filament without substantial adverse effect to suture handling and stiffness when compared to the sutures prepared from polyethylene terephthalate with a denier per filament less than 3.