IP Library Granted Patent US 7,621,892
Granted Patent B2
US 7,621,892 · App. 10/750,427 · Granted Nov 24, 2009

Contrast container holder and method to fill syringes

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Quick Facts
Patent No.
US 7,621,892
App. No.
10/750,427
Granted
Nov 24, 2009
Kind
B2
Abstract

The filling of a syringe can be performed at a faster rate using a filling sequence which expels air from the fill tube before filling the syringe. A similar method is used when changing contrast containers during a filling sequence to ensure that all the air is expelled from the fill tube before filling resumes with the new contrast container. Additionally, by including a contrast container holder that is affixed to an injector head and holds the container near the syringe tip, the filling sequence can be accomplished without requiring the operator to hold the contrast container during the sequence.

Claims (198)

1. A method for performing a filling sequence in a contrast media injector system that uses a fill tube coupling a syringe to contrast media supply to fill the syringe with a desired fill volume of contrast media, the method comprising:

attaching said fill tube to said syringe;

drawing contrast media into the syringe through the fill tube at a first fill rate;

thereafter, automatically expelling substantially all air from the fill tube by automatically reversing the first fill rate and expelling fluid from said syringe, wherein at least some of the contrast media is expelled through the fill tube during the expelling;

thereafter, filling the syringe at a second fill rate to fill the syringe with the desired fill volume of contrast media, wherein the second fill rate is faster than the first fill rate; and

thereafter, injecting contrast media into a patient.

2. The method according to claim 1 wherein the drawing comprises drawing a first amount of contrast media into the syringe, and the expelling comprises expelling substantially all of the first amount of contrast media out of the syringe.

3. The method according to claim 1 , wherein the expelling comprises expelling substantially all air from the syringe.

4. The method according to claim 1 , wherein the expelling is performed by the contrast media injector automatically under control of control circuitry of the injector.

5. The method according to claim 1 , wherein the filling is performed by the contrast media injector automatically under control of control circuitry of the injector.

6. The method according to claim 1 , wherein the expelling and the filling are performed by the contrast media injector automatically under control of control circuitry of the injector.

7. The method of claim 1 , wherein the syringe is oriented such that a discharge tip of the syringe is positioned above a barrel of the syringe during the drawing, the expelling, and the filling.

8. The method of claim 1 , wherein both air and contrast media are expelled through a discharge tip of the syringe during the expelling.

9. A method for changing contrast media containers during a syringe filling sequence, the method comprising:

attaching a fill tube to a syringe;

thereafter, filling a syringe at at least one of a first fill rate and a second fill rate through the fill tube, the fill tube coupled between the syringe and a first contrast container;

thereafter, pausing the filling when the first contrast container is substantially emptied;

thereafter, replacing the first contrast container with a second contrast container;

thereafter, coupling the fill tube between the syringe and the second contrast container;

thereafter, expelling substantially all air from the fill tube coupled between the syringe and the second contrast container wherein at least some of the contrast media is expelled from the syringe, through the fill tube, and into the second contrast container during the expelling; and

thereafter, resuming filling the syringe from the second contrast container at the second fill rate that is faster than the first fill rate.

10. The method according to claim 9 wherein the step of expelling comprises:

expelling a portion of contrast media that was acquired from the first contrast container out of the syringe through the fill tube and into the second contrast container.

11. The method according to claim 9 , wherein the expelling comprises expelling substantially all air from the syringe.

12. The method of claim 9 , wherein the syringe is oriented such that a discharge tip of the syringe is positioned above a barrel of the syringe during the filling, the expelling, and the resuming.

13. The method of claim 9 , wherein both air and contrast media are expelled through a discharge tip of the syringe during the expelling.

14. A method of operation for a contrast media injector system, the method comprising:

automatically drawing an initial volume of medical fluid into a syringe of a contrast media injector system at a first fill rate;

after the drawing, automatically ceasing drawing and commencing expelling at least some of the medical fluid from the syringe; and

thereafter, automatically ceasing expelling and commencing filling the syringe at a second fill rate that is faster than the first fill rate, wherein a total volume of medical fluid in the syringe after the filling is greater than the initial volume.

15. The method of claim 14 , wherein the first fill rate is a rate sufficient to avoid aeration of the medical fluid.

16. The method of claim 14 , wherein the drawing comprises drawing at least 20 ml of the medical fluid into the syringe.

17. The method of claim 14 , wherein the drawing comprises drawing medical fluid through a fill tube and into the syringe.

18. The method of claim 14 , wherein the syringe is oriented such that a discharge tip of the syringe is positioned above a barrel of the syringe during the drawing, the expelling, and the filling.

19. The method of claim 14 , wherein both air and contrast media are expelled through a discharge tip of the syringe during the expelling.

20. A method of performing an automated syringe filling sequence in a contrast media injector, the method comprising:

the injector pulling a first amount of fluid into a syringe of the injector at a first rate;

after the injector pulling the first amount of fluid into the syringe, the injector automatically reversing a direction of a ram of the injector to expel at least a portion of the fluid from the syringe; and

after the injector automatically reversing the direction of the ram, the injector automatically retracting the ram at a second rate faster than the first rate to draw a second volume of the fluid into the syringe.

21. The method of claim 20 , wherein the first rate is slow enough so as not to aerate the fluid.

22. The method of claim 21 , wherein the first volume is a volume sufficient to be visibly noticed by an operator of the injector.

23. The method of claim 22 , wherein the first volume is at least about 20 ml.

24. The method of claim 23 , wherein all air is expelled from the syringe upon completion of the injector automatically reversing the direction of the ram to expel at least a portion of the fluid from the syringe.

25. The method of claim 24 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

26. The method of claim 25 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

27. The method of claim 23 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

28. The method of claim 27 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

29. The method of claim 23 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

30. The method of claim 22 , wherein all air is expelled from the syringe upon completion of the injector automatically reversing the direction of the ram to expel at least a portion of the fluid from the syringe.

31. The method of claim 30 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

32. The method of claim 31 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

33. The method of claim 30 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

34. The method of claim 22 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

35. The method of claim 34 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

36. The method of claim 22 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

37. The method of claim 21 , wherein the first volume is at least about 20 ml.

38. The method of claim 37 , wherein all air is expelled from the syringe upon completion of the injector automatically reversing the direction of the ram to expel at least a portion of the fluid from the syringe.

39. The method of claim 38 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

40. The method of claim 39 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

41. The method of claim 38 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

42. The method of claim 37 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

43. The method of claim 42 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

44. The method of claim 37 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

45. The method of claim 21 , wherein all air is expelled from the syringe upon completion of the injector automatically reversing the direction of the ram to expel at least a portion of the fluid from the syringe.

46. The method of claim 45 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

47. The method of claim 46 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

48. The method of claim 24 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

49. The method of claim 45 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

50. The method of claim 21 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

51. The method of claim 50 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

52. The method of claim 21 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

53. The method of claim 20 , wherein the first volume is at least about 20 ml.

54. The method of claim 53 , wherein all air is expelled from the syringe upon completion of the injector automatically reversing the direction of the ram to expel at least a portion of the fluid from the syringe.

55. The method of claim 54 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

56. The method of claim 55 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

57. The method of claim 54 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

58. The method of claim 53 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

59. The method of claim 58 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

60. The method of claim 53 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

61. The method of claim 20 , wherein the first volume is a volume sufficient to be visibly noticed by an operator of the injector.

62. The method of claim 61 , wherein the first volume is at least about 20 ml.

63. The method of claim 62 , wherein all air is expelled from the syringe upon completion of the injector automatically reversing the direction of the ram to expel at least a portion of the fluid from the syringe.

64. The method of claim 63 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

65. The method of claim 64 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

66. The method of claim 63 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

67. The method of claim 62 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

68. The method of claim 67 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

69. The method of claim 62 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

70. The method of claim 61 , wherein all air is expelled from the syringe upon completion of the injector automatically reversing the direction of the ram to expel at least a portion of the fluid from the syringe.

71. The method of claim 70 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

72. The method of claim 71 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

73. The method of claim 70 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

74. The method of claim 61 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

75. The method of claim 66 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

76. The method of claim 61 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

77. The method of claim 20 , wherein all air is expelled from the syringe upon completion of the injector automatically reversing the direction of the ram to expel at least a portion of the fluid from the syringe.

78. The method of claim 77 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

79. The method of claim 78 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

80. The method of claim 77 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

81. The method of claim 20 , wherein a volume of fluid in the syringe upon completion of the injector automatically retracting the ram is a desired fill volume entered into the injector by an operator of the injector prior to the injector pulling the first amount of fluid into the syringe.

82. The method of claim 81 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

83. The method of claim 20 , wherein the injector is designed such that the syringe is pointing substantially upward during:

the injector pulling the first amount of the fluid into the syringe;

the injector automatically reversing the direction of the ram; and

the injector automatically retracting the ram.

Assignments (8)
RELEASE OF PATENT SECURITY INTERESTS RECORDED AT REEL 032480, FRAME 0001 Recorded Nov 16, 2023
From: DEUTSCHE BANK AG NEW YORK BRANCH, AS COLLATERAL AGENT
To: THERAKOS, INC.; MALLINCKRODT INTERNATIONAL FINANCE S.A.; MALLINCKRODT CB LLC; MALLINCKRODT FINANCE GMBH; MALLINCKRODT US HOLDINGS LLC (F/K/A MALLINCKRODT US HOLDINGS INC.); MALLINCKRODT CARRIBEAN, INC.; MALLINCKRODT US POOL LLC; MNK 2011 LLC (F/K/A MALLINCKRODT INC.); LUDLOW LLC (F/K/A LUDLOW CORPORATION); CNS THERAPEUTICS, INC.; MALLINCKRODT ENTERPRISES HOLDINGS LLC (F/K/A MALLINCKRODT ENTERPRISES HOLDINGS, INC.); MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; LAFAYETTE PHARMACEUTICALS LLC; LIEBEL-FLARSHEIM COMPANY LLC; MALLINCKRODT BRAND PHARMACEUTICALS LLC (F/K/A MALLINCKRODT BRAND PHARMACEUTICALS, INC.); MALLINCKRODT VETERINARY, INC.; MALLINCKRODT US HOLDINGS LLC; IMC EXPLORATION COMPANY; MEH, INC.; MALLINCKRODT HOSPITAL PRODUCTS IP UNLIMITED COMPANY (F/K/A MALLINCKRODT HOSPITAL PRODUCTS IP LIMITED); MALLINCKRODT ARD IP UNLIMITED COMPANY (F/K/A MALLINCKRODT ARD IP LIMITED); OCERA THERAPEUTICS LLC (F/K/A OCERA THERAPEUTICS, INC.); SPECGX LLC; STRATATECH CORPORATION; SUCAMPO PHARMA AMERICAS LLC; VTESSE LLC (F/K/A VTESSE INC.); MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED; MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY (F/K/A MALLINCKRODT PHARMA IP TRADING D.A.C.); INFACARE PHARMACEUTICAL CORPORATION; ST SHARED SERVICES LLC; IKARIA THERAPEUTICS LLC; INO THERAPEUTICS LLC
Reel/Frame 065609/0322 →
RELEASE OF SECURITY INTEREST Recorded Nov 30, 2015
From: DEUTSCHE BANK AG NEW YORK BRANCH, AS COLLATERAL AGENT
To: LIEBEL-FLARSHEIM COMPANY LLC
Reel/Frame 037172/0094 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2014
From: MALLINCKRODT LLC
To: LIEBEL-FLARSHEIM COMPANY LLC
Reel/Frame 034715/0531 →
SECURITY INTEREST Recorded Mar 19, 2014
From: MALLINCKRODT INTERNATIONAL FINANCE S.A.; MALLINCKRODT CB LLC; MALLINCKRODT FINANCE GMBH; MALLINCKRODT US HOLDINGS INC.; MALLINCKRODT CARIBBEAN, INC.; MALLINCKRODT US POOL LLC; MALLINCKRODT INC.; LUDLOW CORPORATION; CNS THERAPEUTICS, INC.; ENTERPRISES HOLDINGS, INC.; MALLINCKRODT ENTERPRISES LLC; MALLINCKRODT LLC; LAFAYETTE PHARMACEUTICALS LLC; LIEBEL-FLARSHEIM COMPANY LLC; MALLINCKRODT BRAND PHARMACEUTICALS, INC; MALLINCKRODT VETERINARY, INC.; MALLINCKRODT US HOLDINGS LLC; IMC EXPLORATION COMPANY; MEH, INC; MALLINCKRODT ENTERPRISES HOLDINGS, INC.
To: DEUTSCHE BANK AG NEW YORK BRANCH
Reel/Frame 032480/0001 →
CHANGE OF LEGAL ENTITY Recorded Aug 16, 2011
From: MALLINCKRODT INC.
To: MALLINCKRODT LLC
Reel/Frame 026754/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 30, 2007
From: LIEBEL-FLARSHEIM COMPANY
To: MALLINCKRODT INC.
Reel/Frame 019092/0367 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 3, 2006
From: LIEBEL-FLARSHEIM COMPANY
To: MALLINCKRODT INC.
Reel/Frame 018044/0598 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2003
From: FAGO, FRANK M.; BERGEN, ROBERT; FARMER, JAMES F.
To: LIEBEL-FLARSHEIM COMPANY
Reel/Frame 014877/0804 →