Ligand for peroxisome proliferator-activated receptor
View Patent ↗The object of the present invention is to provide PPARγ ligand derived from naturally occurring sources and a composition for preventing and/or improving Insulin Resistance Syndrome, diabetes mellitus, obesity or visceral fat obesity comprising the PPARγ ligand as an active agent. The present invention relates to a ligand for peroxisome proliferator-activated receptor which comprises curcumin or its derivatives. The composition according to the present invention, which comprises the PPARγ ligand as an active agent is useful for preventing and/or improving Insulin Resistance Syndrome, diabetes mellitus, obesity or visceral fat obesity.
1. A method for reducing visceral fat, which comprises administering to a subject suffering from type-II diabetes mellitus, hyperinsulinemia, dyslipidemia, hypertension, and/or arteriosclerotic cardiovascular disease, a composition comprising at least one selected from the group consisting of curcumin and a curcuminoid as an active agent, with the intention of reducing visceral fat in said subject.
2. The method according to claim 1 , wherein said composition is in the form of a food or a drink.
3. The method according to claim 1 , wherein said composition is in the form of a pharmaceutical.
4. The method according to claim 1 , wherein said subject is a domestic animal or pet.