Methods and apparatus for non-invasively treating atrial fibrillation using high intensity focused ultrasound
Methods and apparatus are provided for non-invasively treating patent foramen ovale using an ultrasound imaging system and a high intensity focused ultrasound system to selectively target high intensity ultrasound energy on either or both of a patient's septum primum or septum secundum.
1. A method of treating patent foramen ovale comprising:
providing a catheter having a distal portion housing an ultrasound imaging system and a high intensity focused ultrasound system disposed in alignment with the ultrasound imaging system;
disposing the distal portion of the catheter within a patient's body lumen;
operating the ultrasound imaging system to generate an image of a portion of cardiac tissue; and
operating the high intensity focused ultrasound system, guided by the image, to heat or ablate either or both of the patient's septum primum or septum secundum.
2. The method of claim 1 , wherein the body lumen is the aorta.
3. The method of claim 1 , wherein the body lumen is the right atrium.
4. The method of claim 1 , wherein the body lumen is the inferior vena cava.
5. The method of claim 1 , wherein the body lumen is the superior vena cava.
6. The method of claim 1 further comprising generating and displaying a marker corresponding to a focal point of the high intensity focused ultrasound system on the image.
7. The method of claim 1 further comprising modifying a location of the treatment by adjusting a location of a focal point of the high intensity focused ultrasound system.
8. The method of claim 7 wherein the location of the focal point of the high intensity focused ultrasound system is adjusted within a two-dimensional plane orthogonal to an axis of the high intensity focused ultrasound system.
9. The method of claim 7 wherein the location of the focal point of the high intensity focused ultrasound system is adjusted by modifying a location of a depth of the focal point of the high intensity focused ultrasound system.
10. The method of claim 1 further comprising apposing the patient's septum primum and septum secundum noninvasively using drugs, noninvasive procedures, or a combination thereof.
11. The method of claim 1 further comprising increasing contact pressure between the patient's septum primum and septum secundum is noninvasively using drugs, noninvasive procedures, or a combination thereof.