Mousse composition
View Patent ↗A topical mousse composition including an occlusive agent; an aqueous solvent; and an organic cosolvent, wherein the occlusive agent is present in an amount sufficient to form an occlusive layer on the skin.
1. A topical mousse composition, the mousse composition comprising:
(a) an occlusive agent;
(b) an aqueous solvent; and
(c) an organic cosolvent;
wherein the occlusive agent is present in an amount sufficient to form an occlusive layer on the skin.
2. The topical mousse composition according to claim 1 , wherein the occlusive agent comprises petrolatum.
3. The topical mousse composition according to claim 2 , wherein the occlusive agent further comprises a mineral oil and a long chain acid.
4. The topical mousse composition according to claim 1 , wherein the occlusive agent is selected from the group consisting of a mineral oil and grease, a long chain acid, an animal fat and grease, a vegetable fat and grease, and a water insoluble polymer.
5. The topical mousse composition according to claim 1 or 2 , wherein the occlusive agent is present in an amount of approximately 55% by weight or less, based on the total weight of the composition.
6. The topical mousse composition according to claim 5 , wherein the occlusive agent is present in an amount of approximately 10 to 50% by weight, based on the total weight of the composition.
7. The topical mousse composition according to claim 1 , further comprising an effective amount of an emulsifier component.
8. The topical mousse composition according to claim 7 , wherein the emulsifier component is present in an amount of from approximately 1% to 15% by weight, based on the total weight of the composition.
9. The topical mousse composition according to claim 7 , wherein the emulsifier component is present in an amount of from approximately 2% to 5% by weight, based on the total weight of the composition.
10. The topical mousse composition according to claim 7 , wherein the emulsifier component is selected from the group consisting of a non-ionic surfactant, a cationic surfactant, an anionic surfactant, a fatty alcohol, a fatty acid, and fatty acid salts thereof.
11. The topical mousse composition according to claim 10 , wherein the emulsifier component comprises a mixture of a sorbitan ester and a polyoxyethylene fatty alcohol ether.
12. The topical mousse composition according to claim 11 , wherein the emulsifier component further comprises a fatty alcohol, a fatty acid or a fatty acid salt.
13. The topical mousse composition according to claim 1 , wherein the aqueous solvent is present in an amount of approximately 25 to 95% by weight, based on the total weight of the composition.
14. The topical mousse composition according to claim 1 , wherein the organic cosolvent is present in an amount of approximately 0.25% by weight to 50% by weight, based on the total weight of the composition.
15. The topical mousse composition according to claim 1 , wherein the organic cosolvent is present in an amount of approximately 0.5% by weight to 2.0% by weight, based on the total weight of the composition.
16. The topical mousse composition according to claim 14 , wherein the organic cosolvent comprises an alkyl benzoate.
17. The topical mousse composition according to claim 14 , wherein the organic cosolvent is selected from the group consisting of an alkyl ether, an aromatic ether and a cyclic ether.
18. The topical mousse composition according to claim 1 , further comprising an effective amount of an aerosol propellant.
19. The topical mousse composition according to claim 18 , wherein the aerosol propellant is a hydrocarbon and is present in an amount of approximately 2.5 to 20% by weight, based on the total weight of the composition.
20. The topical mousse composition according to claim 1 , further comprising a water-insoluble pharmaceutically active ingredient.
21. The topical mousse composition according to claim 20 , wherein said water-insoluble pharmaceutically active ingredient is selected form the group consisting of an analgesic, an antifungal, an antibacterial, an anesthetic, an antiviral, an antipruritic, an antihistamine, a xanthine, a sex hormone, an anti-inflammatory, and a corticosteroid.
22. The topical mousse composition according to claim 21 , wherein said water-insoluble pharmaceutically active ingredient is an anti-inflammatory.
23. The topical mousse composition according to claim 20 , wherein the pharmaceutically active ingredient is insoluble in both water and the occlusive agent.
24. The topical mousse composition according to claim 20 , wherein the pharmaceutically active ingredient is present in an amount of from approximately 0.005% by weight to approximately 10% by weight, based on the total weight of the composition.
25. The topical mousse composition according to claim 20 , wherein the pharmaceutically active ingredient is present in an amount of from approximately 0.05% by weight to approximately 1% by weight, based on the total weight of the composition.
26. A topical mousse composition, the mousse composition comprising:
(a) petrolatum in an amount of approximately 10 to 50% by weight, based on the total weight of the composition;
(b) an aqueous solvent; and
(c) an organic cosolvent.
27. The topical mousse composition according to claim 26 , further comprising an effective amount of an emulsifier component.
28. The topical mousse composition according to claim 26 , further comprising a water-insoluble pharmaceutically active ingredient.
29. The topical mousse composition according to claim 26 , wherein said water-insoluble pharmaceutically active ingredient is selected form the group consisting of an analgesic, an antifungal, an antibacterial, an anesthetic, an antiviral, an antipruritic, an antihistamine, xanthine, a sex hormone, an anti-inflammatory, and a corticosteroid.
30. The topical mousse composition according to claim 29 , wherein said water-insoluble pharmaceutically active ingredient is an anti-inflammatory.
31. A dispenser, the dispenser comprising:
a topical mousse composition comprising:
(a) an occlusive agent;
(b) an aqueous solvent; and
(c) an organic cosolvent;
wherein the occlusive agent is present in an amount sufficient to form an occlusive layer on the skin.
32. The dispenser according to claim 31 , wherein said occlusive agent in said topical mousse composition comprises petrolatum.
33. The dispenser according to claim 31 , wherein said topical mousse composition further comprises an effective amount of an emulsifier component.
34. The dispenser according to claim 31 , wherein said topical mousse composition further comprises a water-insoluble pharmaceutically active ingredient.
35. The dispenser according to claim 31 , wherein said water-insoluble pharmaceutically active ingredient is selected from the group consisting of an analgesic, an antifungal, an antibacterial, an anesthetic, an antiviral, an antipruritic, an antihistamine, a xanthine, a sex hormone, an anti-inflammatory, and a corticosteroid.
36. The dispenser according to claim 35 , wherein said water-insoluble pharmaceutically active ingredient is an anti-inflammatory.
37. The topical mousse composition according to claim 21 , wherein said water-insoluble pharmaceutically active ingredient is a corticosteroid.
38. The topical mousse composition according to claim 29 , wherein said water-insoluble pharmaceutically active ingredient is a corticosteroid.
39. The dispenser according to claim 35 , wherein said water-insoluble pharmaceutically active ingredient is a corticosteroid.