IP Library Granted Patent US 8,187,234
Granted Patent B2
US 8,187,234 · App. 10/768,571 · Granted May 29, 2012

Pressure activated safety valve with anti-adherent coating

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Quick Facts
Patent No.
US 8,187,234
App. No.
10/768,571
Granted
May 29, 2012
Kind
B2
Abstract

A pressure activated valve comprises a valve housing defining a lumen for receiving bodily fluids therein and a flexible membrane disposed in the valve housing. The flexible membrane includes a slit extending therethrough so that the flexible membrane may be moved between an open and a closed configuration based on fluid pressure within the lumen. A nonthrombogenic coating may be formed on fluid contacting surfaces of the flexible membrane.

Claims (15)

1. A pressure activated valve comprising:

a valve housing defining a lumen for receiving bodily fluids therein;

a flexible member disposed in the valve housing, the flexible member comprising a plurality of peripheral flexible membranes stacked on opposing sides of a central flexible membrane, each of the flexible membranes including at least one slit extending therethrough so that each flexible membrane may be moved between an open and a closed configuration based on fluid pressure within the lumen, wherein when all of the flexible membranes are moved to an open position, the flexible member is open to permit fluid flow through the housing; and

a nonthrombogenic coating formed on fluid contacting surfaces of the flexible member,

wherein each of said peripheral flexible membranes includes a beveled surface for directing fluid toward the slits.

2. The valve according to claim 1 , wherein the nonthrombogenic coating includes a material which comprises at least one of heparin and phosphorylcholine.

3. The valve according to claim 1 , wherein one of a proximally outward and a distally outward face of the flexible membrane includes a fluid directing recess formed therein to direct fluid flow toward the slits of the flexible membranes.

4. The valve according to claim 1 , wherein the nonthrombogenic coating is a flexible polymeric coating.

5. The valve according to claim 1 , wherein the nonthrombogenic coating includes a material which prevents the formation of blood clots.

6. The valve according to claim 1 , wherein the nonthrombogenic coating is a coating comprising at least one of heparin and phosphorylcholine.

7. The valve according to claim 1 , wherein said flexible membranes are formed of silicone.

8. The valve according to claim 1 , further comprising a second nonthrombogenic coating on bodily-fluid-contacting surfaces of the lumen.

9. The valve according to claim 1 , wherein at least one of said at least one slits is linear.

10. The valve according to claim 1 , wherein at least one of said at least one slits is curved.

11. The valve according to claim 1 , wherein each of said flexible membranes is characterized by a minimum thickness, the minimum thickness of said peripheral flexible membranes being less than the minimum thickness of said central flexible membrane.

Assignments (28)
MERGER AND CHANGE OF NAME Recorded Sep 8, 2023
From: NM HOLDING COMPANY, INC.; ANGIODYNAMICS, INC.
To: ANGIODYNAMICS, INC.
Reel/Frame 064840/0964 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2023
From: BOSTON SCIENTIFIC SCIMED, INC.
To: NAMIC/VA, INC.
Reel/Frame 064841/0581 →
CHANGE OF NAME Recorded Sep 8, 2023
From: NAMIC / VA, INC.
To: NAVILYST MEDICAL, INC.
Reel/Frame 064852/0006 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2023
From: WEAVER, KARLA; DICARLO, PAUL
To: SCIMED LIFE SYSTEMS, INC.
Reel/Frame 064840/0606 →
CHANGE OF NAME Recorded Sep 8, 2023
From: SCIMED LIFE SYSTEMS, INC.
To: BOSTON SCIENTIFIC SCIMED, INC.
Reel/Frame 064840/0647 →
MERGER AND CHANGE OF NAME Recorded Sep 8, 2023
From: NAVILYST MEDICAL, INC.; NAVILYST MEDICAL HOLDINGS, INC.
To: NAVILYST MEDICAL HOLDINGS, INC.
Reel/Frame 064840/0850 →
MERGER AND CHANGE OF NAME Recorded Sep 8, 2023
From: NAVILYST MEDICAL HOLDINGS, INC.; NM HOLDING COMPANY, INC.
To: NM HOLDING COMPANY, INC.
Reel/Frame 064840/0936 →
MERGER AND CHANGE OF NAME Recorded Sep 6, 2023
From: NAVILYST MEDICAL, INC.; NAVILYST MEDICAL HOLDINGS, INC.
To: NAVILYST MEDICAL HOLDINGS, INC.
Reel/Frame 064812/0514 →
MERGER AND CHANGE OF NAME Recorded Sep 6, 2023
From: NAVILYST MEDICAL HOLDINGS, INC.; NM HOLDING COMPANY, INC.
To: NM HOLDING COMPANY, INC.
Reel/Frame 064812/0774 →
MERGER AND CHANGE OF NAME Recorded Sep 6, 2023
From: NM HOLDING COMPANY, INC.; ANGIODYNAMICS, INC.
To: ANGIODYNAMICS, INC.
Reel/Frame 064812/0966 →
RELEASE OF SECURITY INTEREST Recorded Jun 8, 2023
From: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
To: NAVILYST MEDICAL, INC.
Reel/Frame 063900/0924 →
RELEASE OF SECURITY INTEREST Recorded Aug 31, 2022
From: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
To: NAVILYST MEDICAL, INC.
Reel/Frame 061363/0508 →
SECURITY INTEREST Recorded Aug 31, 2022
From: NAVILYST MEDICAL, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 060950/0195 →
CONFIRMATORY GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Jun 5, 2019
From: NAVILYST MEDICAL, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 049371/0645 →
RELEASE OF SECURITY INTEREST Recorded Nov 14, 2016
From: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
To: NAVILYST MEDICAL, INC.
Reel/Frame 040614/0834 →
RELEASE OF SECURITY INTEREST Recorded Nov 14, 2016
From: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
To: NAVILYST MEDICAL, INC.
Reel/Frame 040613/0077 →
SECURITY INTEREST Recorded Nov 8, 2016
From: NAVILYST MEDICAL, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 040613/0137 →
RELEASE OF SECURITY INTEREST Recorded Sep 30, 2013
From: JPMORGAN CHASE BANK N.A., AS ADMINISTRATIVE AGENT
To: NAVILYST MEDICAL, INC.
Reel/Frame 031315/0554 →
SECURITY AGREEMENT Recorded Sep 30, 2013
From: NAVILYST MEDICAL, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 031315/0594 →
RELEASE OF SECURITY INTEREST RECORDED AT REEL/FRAME 20507/952 Recorded May 25, 2012
From: GENERAL ELECTRIC CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT
To: NAVILYST MEDICAL, INC. (F/K/A NAMIC/VA, INC.)
Reel/Frame 028273/0944 →
RELEASE OF SECURITY INTEREST RECORDED AT REEL/FRAME 20540/726 Recorded May 25, 2012
From: GENERAL ELECTRIC CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT
To: NAVILYST MEDICAL, INC. (F/K/A NAMIC/VA, INC.)
Reel/Frame 028273/0958 →
SECURITY AGREEMENT Recorded May 23, 2012
From: NAVILYST MEDICAL, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 028260/0176 →
CHANGE OF NAME Recorded Sep 11, 2008
From: NAMIC/VA, INC.
To: NAVILYST MEDICAL, INC.
Reel/Frame 021523/0700 →
SECURITY AGREEMENT Recorded Feb 22, 2008
From: NAMIC / VA, INC.
To: GENERAL ELECTRIC CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT
Reel/Frame 020540/0726 →
SECURITY AGREEMENT Recorded Feb 15, 2008
From: NAMIC / VA, INC.
To: GENERAL ELECTRIC CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT
Reel/Frame 020507/0952 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 14, 2008
From: BOSTON SCIENTIFIC SCIMED, INC.
To: NAMIC / VA, INC.
Reel/Frame 020518/0549 →
CHANGE OF NAME Recorded Jul 26, 2005
From: SCIMED LIFE SYSTEMS, INC.
To: BOSTON SCIENTIFIC SCIMED, INC.
Reel/Frame 016807/0162 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 29, 2004
From: WEAVER, KARLA; DICARLO, PAUL
To: SCIMED LIFE SYSTEMS, INC.
Reel/Frame 014950/0608 →