IP Library › Granted Patent US 7,189,263
Granted Patent B2
US 7,189,263 · App. 10/771,077 · Granted Mar 13, 2007

Biocompatible bone graft material

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Quick Facts
Patent No.
US 7,189,263
App. No.
10/771,077
Granted
Mar 13, 2007
Kind
B2
Abstract

Biocompatible bone graft material having a biocompatible, resorbable polymer and a biocompatible, resorbable inorganic material exhibiting macro, meso, and microporosities.

Claims (27)

1. A biocompatible bone graft material comprising a homogenous composite of biocompatible, resorbable collagen and calcium phosphate, the biocompatible bone graft having macro-, meso-, and microporosity.

2. The bone graft material of claim 1 wherein said collagen is Type I bovine collagen.

3. The bone graft material of claim 1 wherein said phosphate and collagen have a mass ratio of about 90:10 to about 70:30.

4. The bone graft material of claim 3 wherein said phosphate and collagen have a mass ratio of about 85:15 to about 75:25.

5. The bone graft material of claim 1 having up to about 30% by weight of collagen.

6. The bone graft material of claim 1 having up to about 20% by weight of collagen.

7. The bone graft material of claim 1 having up to about 10% by weight of collagen.

8. The bone graft material of claim 1 wetted with a fluid comprising bone marrow aspirate, blood, or saline.

9. The bone graft material of claim 1 having a cylindrical, block, or discoid shape.

10. The bone graft material of claim 9 also comprising a metal mesh.

11. The bone graft material of claim 10 wherein said metal comprises titanium.

12. The bone graft material of claim 1 wherein the bone graft material is shredded.

13. A bone graft for long bone reinforcement in the form of a sleeve, the graft comprising a homogenous composite of biocompatible, resorbable collagen and calcium phosphate, the graft having macro-, meso-, and microporosity.

14. The bone graft of claim 13 further comprising a mesh affixed to a surface of the sleeve.

15. The bone graft of claim 14 wherein said mesh is immersed in the graft.

16. The bone graft of claim 14 wherein the mesh is of titanium, stainless steel, nitinol, a composite polymer, or polyetheretherketone.

17. The bone graft of claim 13 wherein the calcium phosphate and collagen are in a mass ratio of about 90:10 to about 70:10.

18. The bone graft of claim 13 wherein the calcium phosphate and collagen are in a mass ratio of about 85:15 to about 75:25.

19. The bone graft of claim 13 wherein the cross-section of the sleeve is in the shape of a crescent shape moon.

20. The bone graft of claim 13 wherein the calcium phosphate is beta-tricalcium phosphate.

21. A graft for the restoration of bone in the form of a shaped body, the shaped body comprising a homogenous composite of polymer and beta-tricalcium phosphate, the graft having interconnected macro-, meso-, and microporosity; the shaped body being selected to conform generally to a mammalian, anatomical tissue structure; and further comprising a mesh affixed to a side of the composite.

22. The graft of claim 21 wherein the mesh is of titanium, stainless steel, nitinol, a composite polymer, or polyetheretherketone.

23. The graft of claim 21 wherein the polymer is collagen.

24. The graft of claim 21 wherein the body shape is a disk, semi-sphere, semi-tubular, or torus.

25. The graft of claim 21 wherein the body shape conforms to the acetabulum.

26. The graft of claim 21 wherein the beta-tricalcium phosphate and polymer are in a mass ratio of about 90:10 to about 70:10.

27. The graft of claim 26 wherein the beta-tricalcium phosphate and polymer are in a mass ratio of about 85:15 to about 75:25.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 1, 2023
From: ORTHOVITA, INC.
To: STRYKER CORPORATION
Reel/Frame 065735/0360 →
RELEASE OF LIEN IN INTELLECTUAL PROPERTY Recorded Jul 26, 2011
From: LB I GROUP INC.
To: ORTHOVITA, INC. (FOR ITSELF AND AS SUCCESSOR BY MERGER TO VITA LICENSING, INC. AND PARTISYN CORP.); ORTHOVITA INTERNATIONAL SERVICES, INC.; VITA SPECIAL PURPOSE CORP.
Reel/Frame 026648/0422 →
MERGER Recorded Dec 1, 2008
From: VITA LICENSING, INC.
To: ORTHOVITA, INC.
Reel/Frame 021901/0354 →
MERGER Recorded Nov 20, 2008
From: VITA SPECIAL PURPOSE CORP
To: VITA LICENSING, INC.
Reel/Frame 021890/0490 →
SECURITY AGREEMENT Recorded Aug 3, 2007
From: VITA SPECIAL PURPOSE CORP.
To: LB I GROUP INC.
Reel/Frame 019649/0291 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 4, 2004
From: ERBE, ERIK M.; CLINEFF, THEODORE D.; BAGGA, CHARANPREET S.; NAGVAJARA, GINA M.; KOBILISH, ANTONY
To: VITA SPECIAL PURPOSE CORPORATION
Reel/Frame 014691/0400 →