IP Library Granted Patent US 7,538,106
Granted Patent B2
US 7,538,106 · App. 10/773,480 · Granted May 26, 2009

Application of 2-cyano-10- (2-methyl-3- (methylamino)- propyl) phenothiazine or a pharmaceutically acceptable salt as medicament

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Quick Facts
Patent No.
US 7,538,106
App. No.
10/773,480
Granted
May 26, 2009
Kind
B2
Abstract

The present invention relates to the application of 2-cyano-10-(2-methyl-3-(methylamino)-propyl)phenothiazine or a pharmaceutically acceptable salt thereof to produce a medicament intended for the treatment of sleep disorders, anxiety disorders, mood disorders, mixed anxiety-depression disorder, acute and chronic psychotic state, addiction to and withdrawal from a substance, extrapyramidal events induced by antipsychotics, or symptomatic dimensions during acute or chronic psychotic states as monotherapy or in combination with other antipsychotics.

Claims (4)

1. A method of treating a patient for sleep disorders selected from the group consisting of insomnia and sleep apnea comprising the oral or parenteral administration of a therapeutically effective amount of from about 10 mg to about 300 mg of 2-cyano-10-(2-methyl-3-(methylamino)propyl)phenothiazine (I) or a pharmaceutically acceptable salt thereof.

2. The method as set forth in claim 1 wherein said sleep disorder is primary insomnia.

3. The method as set forth in claim 1 wherein said sleep disorder is insomnia related to another mental disorder.

4. The method as set forth in claim 1 wherein said sleep disorder is obstructive sleep apnea. disease is anxiety disorder.

Assignments (4)
MERGER Recorded Jan 19, 2015
From: AVENTIS PHARMACEUTICALS INC.
To: AVENTISUB LLC
Reel/Frame 034781/0334 →
CERTIFICATE OF CONVERSION Recorded Dec 9, 2014
From: AVENTISUB INC.
To: AVENTISUB LLC
Reel/Frame 034566/0976 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 13, 2009
From: DIB, MICHEL; HAMEG, AHCENE
To: AVENTIS PHARMA S.A..
Reel/Frame 022536/0563 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 13, 2009
From: AVENTIS PHARMA S.A.
To: AVENTIS PHARMACEUTICALS INC.
Reel/Frame 022537/0854 →