Use of neurotoxin therapy for treatment of urologic and related disorders related to lowering elevated bladder pressure
View Patent ↗The present invention related to methods for treating neurological-urological conditions, including urinary retention. This is accomplished by administration of a botulinum toxin into the lower urinary tract of a patient with urinary retention, including the bladder or urinary sphincter and the bladder wall.
1. A method for lowering elevated bladder pressure in a patient, the method comprising the step of injecting a therapeutically effective amount of a botulinum toxin type A into the bladder neck of a patient with elevated bladder pressure, thereby lowering the elevated bladder pressure.
2. The method of claim 1 , wherein the step of injection comprises a single injection.
3. The method of claim 1 , wherein the step of injection comprise injecting a gel comprising the botulinum toxin.
4. The method of claim 1 , wherein the step of injecting results in increased bladder capacity.
5. The method of claim 1 , wherein the therapeutically effective amount of botulinum toxin type A is up to 2500 units.
6. The method of claim 1 , wherein the therapeutically effective amount of botulinum toxin type A is about 1.4 IU/kg to 17.1 IU/kg of botulinum toxin type A.
7. The method of claim 1 , wherein the therapeutically effective amount of botulinum toxin type A is 200 IU of botulinum toxin type A.
8. The method of claim 1 , wherein the therapeutically effective amount of botulinum toxin type A is 800 IU of botulinum toxin type A.