IP Library Granted Patent US 7,098,463
Granted Patent B2
US 7,098,463 · App. 10/790,280 · Granted Aug 29, 2006

Three-dimensional dosimeter for penetrating radiation and method of use

Assignee: Heuris Pharma, LLC
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Quick Facts
Patent No.
US 7,098,463
App. No.
10/790,280
Granted
Aug 29, 2006
Kind
B2
Abstract

This invention relates to a method of forming a three-dimensional (3D) dosimetric map in a solid translucent or transparent polymer and to an article of manufacture comprising a polymer formulated to capture data imparted by incident penetrating radiation. The present invention provides a method of preparation of a solid translucent or transparent polymer matrix capable of detecting and displaying a dose or doses of penetrating radiation by forming within the polymeric matrix a 3D dosimetric map which is measurable and quantifiable by various known procedures. The dosimetric map is representative of the 3D distribution of the dose or doses of the penetrating radiation to which the polymer had been exposed and can be quantified at high spatial resolution, thereby providing an accurate, stable, storable record in three dimensions of the radiation exposure or dosing event(s).

Claims (22)

1. A method for detecting radiation comprising the steps of;

a) subjecting a shaped solid dosimeter to a radiation field, said dosimeter comprises a transparent or translucent polymer and one or more reporter compounds dispersed within said dosimeter,

b) analyzing three dimensional data from said dosimeter exposed to said radiation field by evaluating optical properties of said dosimeters using a tomographic process

c) illuminating said dosimeter with a light source;

d) detecting light from said dosimeter;

e) processing said detected light to construct a three dimensional image; and

rotating said dosimeter and repeating steps c, d, and e.

2. The method of claim 1 further comprising the step of:

c. calculating an amount and distribution of radiation received by the dosimeter from said analyzed three dimensional data.

3. The method of claim 1 wherein an absolute dose is calculated in said step c.

4. A method for detecting radiation comprising the steps of;

a. subjecting a shaped solid dosimeter to a radiation field, said dosimeter comprises a transparent or translucent polymer and one or more reporter compounds dispersed within said dosimeter, and

b. analyzing three dimensional data from said dosimeter exposed to said radiation field by evaluating optical properties of said dosimeters using a tomographic process wherein the radiation emits from a radionuclide.

5. The method of claim 4 wherein the radionuclide is selected from the group consisting of radioactive isotopes of iodine, strontium, samarium, yttrium, ruthenium, palladium, cobalt and iridium.

6. A system for detecting radiation comprising:

means for subjecting a shaped solid dosimeter to a radiation field, said dosimeter comprises a transparent or translucent polymer and one or more reporter compounds dispersed within said dosimeter;

means for analyzing three dimensional data from said dosimeter exposed to said radiation field by evaluating optical properties of said dosimeter; and

means for rotating said dosimeter.

7. A system for detecting radiation comprising:

means for subjecting a shaped solid dosimeter to a radiation field, said dosimeter comprises a transparent or translucent polymer and one or more reporter compounds dispersed within said dosimeter;

means for analyzing three dimensional data from said dosimeter exposed to said radiation field by evaluating optical properties of said dosimeter wherein the radiation emits from a radionuclide.

8. The system of claim 7 wherein the radionuclide is selected from the group consisting of radioactive isotopes of iodine, strontium, samarium, yttrium, ruthenium, palladium, cobalt, and iridium.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 18, 2004
From: ADAMOVICS, JOHN A.
To: HEURIS PHARMA, LLC
Reel/Frame 015475/0208 →
Continuity (2)
Provisional Application 6045182600 · Mar 3, 2003
Related Publication 20040211917A1 · Oct 28, 2004