Solubilized CoQ-10 and carnitine
The present invention is directed to compositions and methods of delivery of CoQ-10 and an amino acid solubilized in monoterpenes. Use of monoterpenes as dissolving agents, greatly effects the ability to incorporate greater amounts of bioactive CoQ-10 and the amino acid, such as carnitine, i.e., carnitine tartrate, in formulations, such as soft gel capsules.
1. A composition comprising: coenzyme Q-10 and carnitine; a sufficient quantity of limonene suitable to solubilize said coenzyme Q-10 and carnitine; and an acceptable carrier.
2. The composition of claim 1 , wherein said coenzyme Q-10 is selected from the group consisting of coenzyme Q-10, reduced coenzyme Q-10 and semi-reduced coenzyme Q-10.
3. The composition of claim 1 , wherein said composition is in the form of a solution, an elixir, a suspension, or a caplet.
4. The composition of claim 3 , wherein said caplet is a soft gelatin tablet or capsule.
5. The composition of claim 4 , wherein said soft gelatin tablet or capsule further comprises rice bran oil or beeswax.
6. The composition of claim 1 , wherein said coenzyme Q-10 is solubilized in an amount of at least about 0.1% by weight to about 45% by weight.
7. The composition of claim 6 , wherein said coenzyme Q-10 is solubilized in an amount of least about 5% to about 40% by weight.
8. The composition of claim 1 , wherein said carnitine is solubilized in an amount of at least about 0.1% by weight to about 20% by weight.
9. The composition of claim 8 , wherein said carnitine is solubilized in an amount of at least about 0.5% by weight to about 10% by weight.
10. The composition of claim 1 , further comprising vitamin E.
11. The composition of claim 1 , further comprising a seed oil.
12. The composition of claim 1 , further comprising a fish oil.
13. The composition of claim 1 , further comprising an antioxidant.
14. The composition of claim 4 , wherein said soft gelatin tablet or capsule further comprises an antioxidant.
15. A packaged nutraceutical formulation comprising: coenzyme Q-10 and carnitine, and a sufficient quantity of limonene, wherein said formulation is encapsulated in a gelatin capsule, and instructions for use thereof.
16. The packaged nutraceutical formulation of claim 15 , wherein said coenzyme Q-10 is selected from the group consisting of coenzyme Q-10, reduced coenzyme Q-10 and semi-reduced coenzyme Q-10.
17. The packaged nutraceutical formulation of claim 15 , wherein said carnitine is solubilized in an amount of at least about 0.1% by weight to about 20% by weight.
18. The packaged nutraceutical formulation of claim 17 , wherein said carnitine is solubilized in an amount of at least about 0.5 % by weight to about 10 % by weight.
19. The composition of claim 4 , wherein said coenzyme Q-10 is solubilized in an amount of at least about 0.1% by weight to about 45% by weight.
20. The composition of claim 19 , wherein said coenzyme Q-10 is solubilized in an amount of least about 5% to about 40% by weight.
21. The composition of claim 4 , wherein said carnitine is solubilized in an amount of at least about 0.1% by weight to about 20% by weight.
22. The composition of claim 21 , wherein said carnitine is solubilized in an amount of at least about 0.5% by weight to about 10% by weight.
23. The packaged nutraceutical formulation of claim 15 , wherein said gelatin capsule is a soft gelatin capsule.
24. The packaged nutraceutical formulation of claim 15 , wherein said coenzyme Q-10 is solubilized in an amount of at least about 0.1% by weight to about 45% by weight.
25. The packaged nutraceutical formulation of claim 15 , wherein said coenzyme Q-10 is solubilized in an amount of at least about 0.5% by weight to about 40% by weight.