Satiation devices and methods
View Patent ↗A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.
1. A method of inducing weight loss in a patient, comprising the steps of:
positioning a flow-restrictive device in the stomach;
coupling the flow-restrictive device to tissue of the gastro-esophageal junction region of the stomach; and
causing food ingested by the patient to flow into contact with the flow-restrictive device, the flow-restrictive device causing the ingested food to flow at a rate that is slower than a rate at which the food would flow in the absence of the flow restrictive device.
2. The method of claim 1 , wherein the positioning step includes positioning the flow-restrictive device in the region of the distal end of the esophagus.
3. The method of claim 1 , wherein the flow-restrictive device causes the ingested food to flow from the esophagus into the stomach at a rate that is slower than a rate at which the food would flow in the absence of the flow restrictive device.
4. The method of claim 1 , wherein the flow-restrictive devices causes an accumulation of food upstream of the flow-restrictive device.
5. The method of claim 1 , wherein the flow restrictive device is a pouch.
6. The method of claim 1 , wherein the flow-restrictive device defines a bi-directional flow path in the gastro-esophageal junction region.
7. The method of claim 1 , wherein the coupling step includes coupling the flow-restrictive device to a tissue plication.
8. The method of claim 1 , wherein the flow-restrictive device is self-expandable, and wherein the method includes allowing the flow restrictive device to self-expand within the gastro-esophageal junction region.