Synthetic multiple quaternary ammonium salts
View Patent ↗This invention pertains to novel multiple quaternary ammonium salts and their derivatives represented by the formula: wherein each R 1 , R′ 1 , R 2 , R′ 2 , R 3 , R′ 3 , R 4 or R 5 is independently selected from the group consisting alkyl, aryl, aralkyl and —CH 2 —CH(OR 6 )—CH 2 N + R 1 R 2 R 3 ; wherein one or more R 6 group is selected from the group consisting of: and wherein An − is an anion. This invention also pertains to novel multiple quaternary ammonium salts and their derivatives represented by the formula: wherein each R 1 , R′ 1 , R 2 , R′ 2 , R 3 or R′ 3 group is independently selected from the group consisting of alkyl, aryl, aralkyl and —CH 2 —CH(OR 4 )—CH 2 N + R 1 R 2 R 3 ; wherein one or more R 4 group is selected from the group consisting of: and wherein An − is an anion.
1. A compound of the formula
wherein each R 1 , R′ 1 , R 2 , R′ 2 , R 3 , R′ 3 , R 4 or R 5 is independently selected from the group consisting of alkyl, aryl, aralkyl and —CH 2 —CH(OR 6 )—CH 2 N + R 1 R 2 R 3 An − , wherein any R 1 , R 2 or R 3 group may be the same or different than other R 1 , R′ 1 , R 2 , R′ 2 , R 3 or R′ 3 groups, and wherein each R 6 can be independently selected from the group consisting of H, alkyl and aralkyl, a 2,3-epoxypropyl group having the structure:
and a 3-chloro-2-hydroxypropyl group having the structure:
and wherein An − is an anion, provided that at least one of the R 6 groups is the 2,3-epoxypropyl group or the 3-chloro-2-hydroxypropyl group.
2. The compound of claim 1 , wherein one R 1 group and the R 4 group comprise a single alkyl group having one or more carbons, and wherein the alkyl group forms part of a cyclic structure that further comprises two positively charged nitrogen centers separated by a three-carbon fragment bearing an —OR 6 group.
3. A compound of the formula
wherein each R 1 , R′ 1 , R 2 , R′ 2 , R 3 or R′ 3 group is independently selected from the group consisting of alkyl, aryl, aralkyl and —CH 2 —CH(OR 4 )—CH 2 N + R 1 R 2 R 3 An − , wherein any R 1 , R 2 or R 3 group may be the same or different than other R 1 , R′ 1 , R 2 , R′ 2 , R 3 or R′ 3 groups, and wherein each R 1 can be independently selected from the group consisting of H, alkyl and aralkyl, a 2,3-epoxypropyl group having the structure:
and a 3-chloro-2-hydroxypropyl group having the structure:
and wherein An− is an anion, provided that at least one of the R 4 groups is the 2,3-epoxypropyl group or the 3-chloro-2-hydroxypropyl group.
4. The compound of claim 3 , wherein the R 1 and R′ 1 groups comprise a single alkyl group having one or more carbons, and wherein said alkyl group forms part of a cyclic structure that further comprises two positively charged nitrogen centers separated by a three-carbon fragment bearing an —OR 4 group.
5. The compound of claim 3 wherein the one or more R 4 groups is a 2,3-epoxypropyl group.